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Titlebook: Renal Tumors of Childhood; Biology and Therapy Kathy Pritchard-Jones,Jeffrey S. Dome Book 2014 The Editor(s) (if applicable) and The Author

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Treatment of Relapsed Wilms Tumor,groups have evaluated the role of different therapeutic strategies in an attempt to improve the outcomes of patients with recurrent WT. Therapy for these patients depends on characteristics of their primary disease, extent of previous therapy, and time from initial diagnosis to relapse.
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Genetic Predisposition to Wilms Tumour,he 11p15-overgrowth disorders, it has emerged that only a subset of individuals are at increased risk of Wilms tumour. The discovery of further Wilms predisposition alleles is set to continue and will improve our ability to identify and manage those at increased risk of Wilms tumour.
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Biological Prognostic Factors in Wilms Tumors, in a second population of patients. Furthermore, prognostic factors are dependent on the treatment used in the population in which they are identified. Thus, as therapy changes from study to study, so too can prognostic factors change, so they must be constantly reassessed. Examples of these princi
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Molecular-Targeted Therapy for Pediatric Renal Tumors,eral neuropathy and bone marrow suppression. Similarly, nephrectomy with or without chemotherapy, a second widely used therapy for Wilms’ tumor, automatically implies a stage I chronic kidney disease (CKD) status. It is becoming increasingly clear that Wilms’ tumor survivors demonstrate “abnormal” r
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,Radiotherapy for Wilms’ Tumour and Other Childhood Renal Cancers,ssible after initial clinical evaluation and diagnostic staging with computed tomography (CT) and ultrasound scanning. This approach without any preoperative therapy facilitates the adoption of a risk-adapted multi-modality treatment based upon a combination of factors that includes age, tumour weig
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