Titlebook: Regulatory T Cells and Clinical Application; Shuiping Jiang Book 2008 Springer-Verlag New York 2008 Asthma.T cell.Transplantation.allergy.

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CD4+Foxp3+Regulatory T Cells in Immune Tolerance-occurring CD4. Treg cells (nTreg) represent a major lymphocyte population maintaining dominant self-tolerance and controlling a variety of pathological immune responses. These nTreg cells specifically express Foxp3, a transcription factor that plays a critical role in their development and function

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CD4+CD25+ Regulatory T Cells as Adoptive Cell Therapy for Autoimmune Disease and for the Treatment oeveloped therapeutic approaches to tackle systemic and organ-specific autoimmune diseases, and treatment with general immunosupressants may soon be replaced by novel therapies based upon this research. Recently, interest in the field of regulatory T cells along with accumulated information that thes

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Natural CD4,CD25, Regulatory T Cells in Regulation of Autoimmune Diseaseign antigens. However, one inevitable consequence of TCR diversity is the generation of self-reactive TCRs creating the potential for autoimmune disease. To balance this, the immune system has developed the processes of central and peripheral tolerance to deter the generation of self-reactive T cell

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laxative

CD4+CD25+ Regulatory T Cells and TGF-Beta in Mucosal Inflammation. Indeed the abrogation of the TGF-beta signaling in immune cells leads to autoimmunity and inflammation in several organs including the gut. TGF-beta acts at multiple levels to maintain the immune system in check. However, TGF-beta has been recently shown to play a key role in the peripheral genera

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Regulatory T Cells in Transplantationugs to inhibit immune responses. These approaches require life-long treatment and suppress the entire immune system non-specifically exposing the patient to increased risks of cancer and infection. Even then long-term graft survival is not guaranteed. Evidence that regulatory T cells can control rej

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inflate