Titlebook: Regulatory Mechanisms of Intracellular Membrane Transport; Sirkka Keränen,Jussi Jäntti Book 20041st edition Springer-Verlag Berlin Heidelb

anthropologist

Phosphoinositides and membrane traffic in health and disease,ntified as precursors of second messengers. In particular, PtdIns 4,5-bisphosphate (PtdIns45P.), initially the most studied of the PIs, was shown to be the substrate of a PI-specific phospholipase C (PI-PLC), which upon agonist stimulation generates the water-soluble inositol 1,4,5-trisphosphate and

refraction

Regulation of exocytotic events by centrosome-analogous structures,tood in the context of their function in the organisation of the mitotic spindle, spindle positioning via astral microtubule organisation, and regulation of cell cycle checkpoints (Doxsey 2001; Pereira and Schiebel 2001). However, cytological studies performed between 1960 and 1980 depict the involv

Moderate

可商量

Regulating membrane curvature,f curvature in their bilayers? A long-standing concept is that membrane curvature can be induced by assembly of a protein coat onto one side of the bilayer. Recent studies indicate that lipids too can serve as the molecular workers in accomplishing the structural changes needed to deform cellular membranes.

草本植物

mortgage

Molecular mechanisms in clathrin-mediated membrane budding,it is now clear that although clathrin, AP-1 and AP-2 are key components of these processes, complex protein machineries are necessary to regulate many of the fundamental processes in CCV formation and cargo selection at both the plasma membrane and the TGN.

心胸开阔

,The function of Sec1/Munc18 proteins – Solution of the mystery in sight?,del, based on increasing experimental evidence that the key function of SM proteins is to bridge the Rab-GTPase dependent machineries of transport vesicle tethering and the SNARE apparatus responsible for vesicle docking and fusion.

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持久

Phosphoinositides and membrane traffic in health and disease, that are known to specifically bind the various PIs, such as FYVE fingers, and PH, PX and ENTH domains, have increased dramatically over just the past few years. By interacting with these protein domains, membrane PIs can control actin cytoskeleton remodelling, vesicle coat assembly, and signalling

松软

1610-2096 proteins and SNARE molecule phosphorylation in exocytosis, endocytosis and membrane fusion. In addition, the role of lipids in vesicle formation and membrane fusion, and some specialized cell biological denovo membrane generation processes are discussed. .978-3-642-06095-3978-3-540-44476-3Series ISSN 1610-2096 Series E-ISSN 1610-6970