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Titlebook: Regulatory Mechanisms of Intracellular Membrane Transport; Sirkka Keränen,Jussi Jäntti Book 20041st edition Springer-Verlag Berlin Heidelb

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书目名称Regulatory Mechanisms of Intracellular Membrane Transport
编辑Sirkka Keränen,Jussi Jäntti
视频video
概述First book in the field of membrane transport with a focus on the regulation of membrane functions rather than on the mechanics.Includes supplementary material:
丛书名称Topics in Current Genetics
图书封面Titlebook: Regulatory Mechanisms of Intracellular Membrane Transport;  Sirkka Keränen,Jussi Jäntti Book 20041st edition Springer-Verlag Berlin Heidelb
描述.This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular networks that govern these processes. Understanding of regulatory processes and participating molecules are likely to reveal global cellular regulatory circuits that couple membrane trafficking with other cellular functions. Such cell biological features are only starting to emerge. This book puts special emphasis on such mechanisms and processes. The contents discusses the role of coat proteins, tethering complexes, small rab GTPases, Sec1-family proteins and SNARE molecule phosphorylation in exocytosis, endocytosis and membrane fusion. In addition, the role of lipids in vesicle formation and membrane fusion, and some specialized cell biological denovo membrane generation processes are discussed. .
出版日期Book 20041st edition
关键词Exocytosis/Endocytosis; Intracellular Membrane Transport; Membrane Budding and Fusing; SNAREs; Tethering
版次1
doihttps://doi.org/10.1007/b11156
isbn_softcover978-3-642-06095-3
isbn_ebook978-3-540-44476-3Series ISSN 1610-2096 Series E-ISSN 1610-6970
issn_series 1610-2096
copyrightSpringer-Verlag Berlin Heidelberg 2004
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1610-2096 plementary material: .This book deals with the molecular mechanisms of membrane trafficking, a central eukaryotic cell biological process. In the post-genomic era many essential molecules involved in intracellular membrane/protein transport are emerging. A huge task now is to compile the molecular n
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Molecular mechanisms in clathrin-mediated membrane budding,network (TGN) where they function in protein transport from the secretory pathway to the endosomal/lysosomal system. It has been long thought that clathrin and the clathrin adaptors 1 (AP-1) and 2 (AP-2) could define a minimal machinery for the formation of CCVs and the selection of cargo. However,
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Regulating membrane curvature,esis, and creation of the high-curvature vesicles and tubules that mediate cargo transport along the endo- and exocytic pathways. Yet membrane bilayers are stabilized against deformations by a powerful hydrophobic effect. Moreover, the various membrane-bound organelles of a cell are composed of diff
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Functions of Rab GTPases in organelle biogenesis,d hydrolysis by Rab are harnessed to recruit and activate specific effector proteins that regulate vesicle tethering and fusion, cargo sorting, and cytoskeleton-dependent organelle transport. We review recent progress in understanding how Rab GTPases are regulated and how they regulate membrane traf
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