Titlebook: Regulation of Membrane Na+-K+ ATPase; Sajal Chakraborti,Naranjan S Dhalla Book 2016 Springer International Publishing AG, part of Springer

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Myocardial Na+ K+-ATPase and SERCA: Clinical and Pathological Significance From a Cytological PerspeSERCA in these processes. Facts are considered from a cytological, pathological, and clinical perspective with an accent to new therapeutic strategies. The aim of this contribution is an overview of functional results in a structural context.

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Uncoupling of P-Type ATPasesependent activity of the Na.,K.-ATPase, uncoupling Na.- from Na.,K. exchange. Here we provide basic information on the function and mechanism of P-type pumps. In addition, we review recent developments on the drug-mediated uncoupling of sarcoplasmic reticulum Ca.-ATPase and Na.,K.-ATPase.

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Book 2016and β- subunits. At present four different α- (α-1,α-2,α-3 and α-4) and three β- (β-1, β-2, and β-3) isoforms have been identified in mammalian cells and their differential expressions are tissue specific. Regulation of Na.+.-K.+ .ATPase activity is an important but a complex process, which involves

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Na+/K+-ATPase: A Perspectiven ATP. It plays an important role in regulating the ionic homeostasis and maintaining membrane potential. Additionally, NKA plays a crucial role in driving a variety of secondary transport processes such as Na.-dependent glucose and amino acid transport..NKA is composed of α and β subunits, which ha

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Na/K-ATPase and Its Role in Signal Transductionout of eukaryotic cells at the expense of ATP. The efforts of numerous investigators during the last two decades have revealed several important non-pumping functions of Na/K-ATPase. This chapter focuses on the molecular mechanism of Na/K-ATPase-mediated signal transduction and its potential regulat

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Calcium Controls the P2-ATPase Mediated Homeostasis: Essential Role of NaAFkDa mass), for the ubiquitous P2-ATPase (and 80 kDa HAF solely for the gastric H/K-ATPase) is essential for P2-ATPase function. The NaAF and HAF function as the allosteric operator-cum gate-keeper of the dual channel P2-ATPase system (where mirror-image orientation of the two α-subunits serves as th