Titlebook: Regulation of Immune Gene Expression; Marc Feldmann,Andrew McMichael Book 1986 The Humana Press Inc. 1986 Antigen.DNA.chromosome.evolution

昏迷状态

Functional Characterization of Several Steric Domains of the Murine Thy-1 and LFA-1 Moleculeseral groups of structures that participate in T-cell activation. These include the molecules involved in T-cell antigen recognition (i.e. T3, T-cell receptor), several non-clonally distributed adhesion molecules (i.e. L3T4, Lyt-2, 3, LFA-1) whose function is to strengthen cell-cell interactions, and

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政府

Murine T-Cell Receptor Genes and the Problems of Cellular Recognition and Repertoire Selectiondistance of elucidating the basic mechanism of T-cell recognition, that is the receptor-1igand interaction, and also should help to illuminate the role of the thymus in T-cell differentiation. The nature of the ligand itself is also being scrutinized in this volume by Schwartz, Bersofsky and others.

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Organisation and Expression of Human T Cell Receptor Genesndicate that the T. molecule confers antigen and MHC binding specificity to a T cell (see, for example, ref. 4). However, it is clear that other surface molecules are also involved in T cell activation in response to antigen. Most notable amongst these is the T3 glycoprotein which is apparently phys

Dedication

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Working-Memory

A Chromosomal Inversion Generates a Functional T Cell Receptor β Chain Geney a variable (V) and a constant (C) gene. The Vβ gene is composed of three gene segments designated variable (Vβ), diversity (Dβ) and joining (Jβ). The V, D and J gene segments are separate in the germline and brought together by DNA-rearrangements during T-lymphocyte differentiation to form a compl

Keratin

Polymorphism in the HLA-D Regionclustering of CG dinucleotides, along with a high level of G & C nucleotides. However, these features are not particularly associated with the polymorphic DQα and DPα chain exons. Some specific DNA sequences are conserved in polymorphic exons from both human and mouse class I and class II genes.

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Murine T-Cell Receptor Genes and the Problems of Cellular Recognition and Repertoire Selectione of the thymus in T-cell differentiation. The nature of the ligand itself is also being scrutinized in this volume by Schwartz, Bersofsky and others. This brief manuscript will attempt to summarize some of the things we know and don’t know about these issues and discuss some of the approaches that we have taken in trying to address them.