Titlebook: Regenerative Medicine and Brain Repair; Philip V. Peplow,Bridget Martinez,Thomas A. Gennar Book 2024 The Editor(s) (if applicable) and The

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Endogenous In Situ Tissue Regeneration Using Inductive Bioscaffolds After Acute Brain Injury,n. .: ECM-based inductive bioscaffolds have been shown to induce a tissue regeneration response in tissue cavities caused by acute brain injuries. They supply inductive cues to attract immune cells, neural cells, as well as endothelial cells into the tissue cavity, while providing a structural suppo

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Alginate Nanofiber Scaffolds for Amyotrophic Lateral Sclerosis,romote the survival of motor neurons and improve motor function in animal models of ALS. Additionally, we have shown that alginate nanofibers cross-linked with strontium had the highest loading efficiency at 59.9% and loaded the most moles of methylene blue per mg of nanofiber at 2.9 nmol/mg when co

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Developing High-Fidelity In Vitro Models of Traumatic Brain Injury to Test Therapeutic Biomaterialsapter is to review the current state of the art in modelling TBI using in vitro model systems which replicate complex pathological processes of TBI, can be interfaced with biomaterials, provide detailed histological and functional readouts, whilst offering ease of use in the laboratory. .: Searches

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Strategies to Upgrade the Stem Cell Application for Brain Transplantation,nson’s, Alzheimer’s, and Huntington’s disease. However, success has been highly limited by poor survival, migration, differentiation, and functional integration of the transplanted cells. .: A thorough literature review was performed on PubMed and Web of Science using the keywords “stem cell brain t

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Neural Stem Cell Intervention in Traumatic Brain Injury,etabolic changes, necrosis, excitotoxicity, and neuroinflammation. These processes further intensify the neural injury induced by TBI. Several treatment strategies that are aimed at different TBI features have been proposed and tested in clinical trials. Yet no approved effective drug has been ident