书目名称 | Regenerative Medicine and Brain Repair |
编辑 | Philip V. Peplow,Bridget Martinez,Thomas A. Gennar |
视频video | |
概述 | Presents updates on clinical trials of stem cell transplantation in brain disorders.Discusses the latest advances of regenerative medicine and tissue engineering for brain repair.Written by world-reno |
丛书名称 | Stem Cell Biology and Regenerative Medicine |
图书封面 |  |
描述 | This book presents the latest knowledge, trends, and advances in cell transplantation and innovations in developing microspheres, 3D biomaterial constructs to enhance transfer, and cell survival to specific regions of the brain. Neurodegenerative diseases and brain injury are increasing. Medications currently only temporarily reduce some of the symptoms but do not cure or delay progression of the disease. Development of effective treatments dramatically improves the independent living and quality of life of patients. Cell transplantation strategies offer an approach to facilitating brain repair, but efficacy is often limited by low in vivo survival rates of cells that are injected in suspension. Transplanting cells that are attached to or encapsulated within a biomaterial construct has the advantage of maintaining cell-cell and cell-material interactions and improving cell survival in vivo. Biomaterials that have been used in preclinical studies to assist with in vivo cell transfer and survival include heparin-chitosan microspheres, poly(lactic-co-glycolic acid) microspheres, RADA 16 microspheres, poly(desaminotyrosyl tyrosine ethyl ester carbonate) microscale scaffolds, carbon nan |
出版日期 | Book 2024 |
关键词 | Biomaterials; Central Nervous System; Brain Injury; Neurodegenerative Disorders; Neurotrophic factors; St |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-031-49744-5 |
isbn_softcover | 978-3-031-49746-9 |
isbn_ebook | 978-3-031-49744-5Series ISSN 2196-8985 Series E-ISSN 2196-8993 |
issn_series | 2196-8985 |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |