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Titlebook: Recent Developments in Mass Spectrometry in Biochemistry and Medicine; Volume 1 Alberto Frigerio Book 1978 Plenum Press, New York 1978 Mass

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发表于 2025-3-21 18:14:38 | 显示全部楼层 |阅读模式
书目名称Recent Developments in Mass Spectrometry in Biochemistry and Medicine
副标题Volume 1
编辑Alberto Frigerio
视频video
图书封面Titlebook: Recent Developments in Mass Spectrometry in Biochemistry and Medicine; Volume 1 Alberto Frigerio Book 1978 Plenum Press, New York 1978 Mass
出版日期Book 1978
关键词Mass Spectrometry; biochemistry; biology; chemistry; medicine; metabolism; pharmacology
版次1
doihttps://doi.org/10.1007/978-1-4613-3991-5
isbn_softcover978-1-4613-3993-9
isbn_ebook978-1-4613-3991-5
copyrightPlenum Press, New York 1978
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The Use of GC-MS in Perinatal Pharmacology: The Metabolism and Pharmacokinetics of Analgesic Drugs izing the lower part of the body. The drug of choice for this at present is bupivacaine. Table 1 lists the analgesic procedures used for the 845 deliveries during the year 1976 at St. Mary’s Hospital, London and shows that some 70% of mothers opted for one of the above treatments, compared with less than 20% who had no analgesic drugs.
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,Studies on the Measurement of α-Methyldopa in Pregnant Women and the Newborn Infant,ivity of the former method make it the more suitable for α-methyldopa determinations in small sample volumes (0.1 ml) and at low concentrations..Confirmation of the placental transfer of α-methyldopa is presented, together with data on the urinary excretion in infants during the first 40 h of life.
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,Comparative , Metabolism of Δ,-tetrahydrocannabinol (Δ,-THC), cannabidiol (CBD) and cannabinol (CBN. Glucuronide formation was a major metabolic route for CBD and CBN. These compounds also produced mono- and di-hydroxy metabolites, acids and hydroxy acids but differed from Δ.-THC in that side-chain acid formation was a major bitrans. formation route for CBD in mouse and benzylic rather than allylic hydroxylation dominated CBN metabolism.
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Identification and Quantification of Gamma-Aminobutyric Acid in Human Cerebrospinal Fluid by Gas Chpatients with no organic neurological disease no GABA was found in the CSF, although the assay used in these studies permitted the detection of GABA at a concentration of 100 pg per assay tube. In some neurological diseases GABA levels were detected in the range of 0–100 ng per ml of CSF.
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A New Derivatization Approach for the Determination of Prostaglandin A1 by Mass Fragmentography,s pyrrolidine, propylenimine, morpholine or hexamethylenimine which give the corresponding pyrrolidyl-, propyleniminyl-, morpholyl-, or hexamethyleniminyl- PGA (TMS). derivatives, respectively, all of them also giving a base peak at M-173.
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Distribution in Brain Areas of Carbamazepine and Carbamazepine-10,11-epoxide in 6-Hydroxydopamine P as reserpine, a-methylparatyrosine and parachlorophenylalanine (1–4). These findings, together with reports on the anticonvulsant activity of two amine precursors, 1-dopa and 5-hydroxytryptophan (4, 5), and d-amphetamine (3), have led to the suggestion that brain monoamines may play a role in seizure susceptibility
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Chemical Ionization Techniques for the Analysis of Labile Compounds: 1,3-bis-(2-chloroethyl)-1-nitr however, by the lack of a sensitive universal detection system. Direct probe chemical ionization (ci) techniques also employ mild sample handling conditions and provide sensitive qualitatively significant mass spectral data (1–5).
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