Titlebook: Recent Advances in the Epidemiology and Prevention of Gallstone Disease; Proceedings of the S L. Capocaccia,G. Ricci,L. Lalloni Conference

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The GREPCO studies: methodology, prevalence and incidence datay of the epidemiology of gallstone disease. At that time most of the available information was derived from autopsy and clinical series. The few epidemiological studies performed by oral cholecystectomy in representative samples of free-living subjects had been carried out in populations known to be

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The natural history of gallstones: the GREPCO experienceases [1–7]. Only in one study [8] were 123 subjects identified as having gallstones by cholecystographic screening of a healthy population and followed prospectively for up to 20 years. These, however, were mainly white American faculty members of the University of Michigan and extrapolation of the

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The outcome of gallstone disease in symptomatic and asymptomatic patients are the imprecise risk factors for the development of the disease, the often long latency period between the presence of stones and the onset of symptoms and the clinical difficulties associated with an accurate diagnosis of upper abdominal gastrointestinal disease. For many years, patients with ga

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Prevalence of gallstone disease in thalassaemia minorvalve-induced haemolysis [6]. In this which is a former malaria district over 10% of the population is formed by heterozygotes with .-thalassaemia trait. However, this being a condition which is found all over the world, it is possible to calculate that there are no fewer than 5 million carriers of

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