Titlebook: Recent Advances in Epilepsy Research; Devin K. Binder,Helen E. Scharfman Book 2004 The Editor(s) (if applicable) and The Author(s), under

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The Role of BDNF in Epilepsy and Other Diseases of the Mature Nervous System,ted in areas implicated in epileptogenesis, and interference with BDNF signal transduction inhibits the development of the epileptic state. Further study of the cellular and molecular mechanisms by which BDNF influences cell survival and excitability will likely provide novel concepts and targets for the treatment of diverse CNS diseases.

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Malformations of Cortical Development: Molecular Pathogenesis and Experimental Strategies,ene mutations result in abnormal cortical cytoarchitecture. The pathogenesis of MCD such as focal cortical dysplasia, hemimegalencephaly, and polymicrogyria, remains unknown. A variety of new techniques including cDNA array analysis now allow for analysis of gene expression within MCD.

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Functional Implications of Seizure-Induced Neurogenesis,, and their often surprising functional implications. The emphasis will be on the granule cells of hippocampus, because they are perhaps more relevant to epilepsy than other areas in which neurogenesis occurs throughout life, the olfactory bulb and subventricular zone. In particular, the following questions will be addressed:

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Recent Advances in Epilepsy Research978-1-4757-6376-8Series ISSN 0065-2598 Series E-ISSN 2214-8019

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https://doi.org/10.1007/978-1-4757-6376-8GABA; Nervous System; brain; cytokine; glutamate receptor; lead; neurobiology; receptor; research

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