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Titlebook: Recent Advances in Epilepsy Research; Devin K. Binder,Helen E. Scharfman Book 2004 The Editor(s) (if applicable) and The Author(s), under

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发表于 2025-3-21 16:13:57 | 显示全部楼层 |阅读模式
书目名称Recent Advances in Epilepsy Research
编辑Devin K. Binder,Helen E. Scharfman
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Recent Advances in Epilepsy Research;  Devin K. Binder,Helen E. Scharfman Book 2004 The Editor(s) (if applicable) and The Author(s), under
描述Epilepsy research has entered an exciting phase as advances in molecular analysis have supplemented .in vitro. and. in vivo. electrophysiologic and phenotypic characterization. .Recent Advances in. .Epilepsy Research. sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. .Key features: neurogenetics of seizure disorders, new developments in cellular and molecular neurobiology of seizure disorders, the role of growth factors in seizures, new advances in the roles of metabotropic glutamate receptors and GABA receptors and transporters, gap junctions, neuroimmunology of epilepsy, malformations of cortical development, neurogenesis, new animal models of epilepsy and the use of brain stimulation to treat epilepsy. This book should be of interest to a wide variety of audiences, including graduate students in neurobiology and related disciplines, neuroscientists, medical students, neurologists, neurosurgeons, and industry including pharmaceutical companies and medical device companies. There are many ideas in this book that will lead ingenious innovators in aca
出版日期Book 2004
关键词GABA; Nervous System; brain; cytokine; glutamate receptor; lead; neurobiology; receptor; research
版次1
doihttps://doi.org/10.1007/978-1-4757-6376-8
isbn_softcover978-1-4419-3418-5
isbn_ebook978-1-4757-6376-8Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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发表于 2025-3-21 23:09:01 | 显示全部楼层
0065-2598 gic and phenotypic characterization. .Recent Advances in. .Epilepsy Research. sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. .Key features: neurogenetics of seizur
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Vascular Endothelial Growth Factor (VEGF) in Seizures:,eability, and inflammation. In brain, receptors for VEGF have been localized to vascular endothelium, neurons, and glia. VEGF is upregulated after hypoxic injury to the brain, which can occur during cerebral ischemia or high-altitude edema, and has been implicated in the blood-brain barrier breakdow
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Role of the GABA Transporter in Epilepsy,t largely from blocking this reuptake. However, there is another side to the GABA transporter, contributing to GABA release by reversing in response to depolarization. We have recently shown that this form of GABA release is induced by even small increases in extracellular [K.], and has a powerful i
发表于 2025-3-23 02:32:16 | 显示全部楼层
GABA and Its Receptors in Epilepsy,s that are ligand-operated on channels and the G-protein-coupled metabotropic GABA. receptors. Impairment of GABAergic transmission by genetic mutations or application of GABA receptor antagonists induces epileptic seizures, whereas drugs augmenting GABAergic transmission are used for antiepileptic
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Role of the Depolarizing GABA Response in Epilepsy,ion of the nervous system. Thus 2 important criteria for a candidate convulsant mechanism are that the mechanism is compatible with normal neural functioning, and that the mechanism can produce rapid deviations from normal function. For example, the blockade of GABA-mediated inhibition is a robust a
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