Titlebook: Recent Advances in Epilepsy Research; Devin K. Binder,Helen E. Scharfman Book 2004 The Editor(s) (if applicable) and The Author(s), under

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Gap Junctions, Fast Oscillations and the Initiation of Seizures,tions. Rather, we shall argue for a role for a newly described sort of gap junction, located between the proximal axons of principal neurons. Such axon-axon gap junctions promote epileptogenesis not so much by enhancing synchrony, as by providing pathways for the direct spread of action potentials b

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Functional Role of Proinflammatory and Anti-Inflammatory Cytokines in Seizures, where seizures initiate d spread. These molecules are released and interact with specific receptors on neurons. Since various cytokines have been shown to affect neuronal excitability, this led to the hypothesis that they may have a role in altering synaptic transmission in epileptic conditions. In

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Using the Immune System to Target Epilepsy,s is the common feature of a diverse collection of disease syndromes collectively called the epilepsies. The epilepsies are estimated to affect 1–2% of the population, with the most common form being temporal lobe epilepsy, which accounts for 40% of all types. The underlying cause of this form of ep

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Malformations of Cortical Development: Molecular Pathogenesis and Experimental Strategies,nical association with epilepsy in infants, children, and adults. Despite multiple anti-epileptic drugs (AEDs), treatment of epilepsy associated with MCD may require cortical resection performed to remove the cytoarchitecturally abnormal region of cortex. Single genes responsible for distinct MCD in

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Book 2004enotypic characterization. .Recent Advances in. .Epilepsy Research. sets forth a series of chapter reviews by researchers involved in these advances. This volume is a composite profile of some exciting recent investigations in select areas of enquiry. .Key features: neurogenetics of seizure disorder