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Titlebook: Ras Superfamily Small G Proteins: Biology and Mechanisms 1; General Features, Si Alfred Wittinghofer Book 2014 Springer-Verlag Wien 2014 GT

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书目名称Ras Superfamily Small G Proteins: Biology and Mechanisms 1
副标题General Features, Si
编辑Alfred Wittinghofer
视频video
概述Cell biology and protein science in its purest form.Focus of this volume lies on signal transduction.Together with volume 2 a must have for all researchers studying small G-proteins.Includes supplemen
图书封面Titlebook: Ras Superfamily Small G Proteins: Biology and Mechanisms 1; General Features, Si Alfred Wittinghofer Book 2014 Springer-Verlag Wien 2014 GT
描述.This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins..Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field..
出版日期Book 2014
关键词GTPases, GTP-binding; cell signaling; molecular switch; protein imaging; spatiotemporal regulation; vesic
版次1
doihttps://doi.org/10.1007/978-3-7091-1806-1
isbn_softcover978-3-7091-1988-4
isbn_ebook978-3-7091-1806-1
copyrightSpringer-Verlag Wien 2014
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https://doi.org/10.1007/978-3-7091-1806-1GTPases, GTP-binding; cell signaling; molecular switch; protein imaging; spatiotemporal regulation; vesic
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Evolution of the Ras Superfamily of GTPasesc GTP-binding site. The Ras superfamily of small GTP-binding proteins is essential to regulate the cellular organization and signaling in cells. Members of this superfamily contain a structurally and mechanistically preserved GTP-binding core, with considerable functional and sequence divergence. In
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The Structure of the G Domain of the Ras Superfamilycreased tremendously. As of February 2014, 555 structures of Ras-superfamily proteins have been deposited in the protein databank (PDB), either in uncomplexed form or bound to effectors or other regulatory proteins. The 751 chains contain either GTP or a GTP analogue (431 chains) and GDP (320 chains
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