找回密码
 To register

QQ登录

只需一步,快速开始

扫一扫,访问微社区

Titlebook: Radiolabeled Monoclonal Antibodies for Imaging and Therapy; Suresh C. Srivastava Conference proceedings 1988 Springer Science+Business Med

[复制链接]
查看: 55632|回复: 59
发表于 2025-3-21 18:01:37 | 显示全部楼层 |阅读模式
书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy
编辑Suresh C. Srivastava
视频video
丛书名称NATO Science Series A:
图书封面Titlebook: Radiolabeled Monoclonal Antibodies for Imaging and Therapy;  Suresh C. Srivastava Conference proceedings 1988 Springer Science+Business Med
描述The advent of hybridoma technology leading to the successful produc­ tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations. These highly specific reagents have essentially replaced the polysera of the earlier days. The successful demonstration of the many wide ranging capabilities of the monoclonal antibody technique has already begun to exert an enormous impact on diverse areas of research in basic science and medicine. In particular, the potential of monoclonal antibodies to serve as carriers for selective targeting of radionuclides to tumors for diagnosis or therapy, has stimulated an intense surge of research interest and even revived hopes of realizing Ehrlich‘s concept of the "magic bullet". Indeed, the technology appears to be on the threshold of a revolution in diagnosing and treating malignant disease. Much work remains to be done, however, and even though the progress has been impressive, results to date have shown only moderate success. There is no question that the limited success we have achieved thus far is merely a prelude to the many more exciti
出版日期Conference proceedings 1988
关键词antibody; antigen; imaging
版次1
doihttps://doi.org/10.1007/978-1-4684-5538-0
isbn_softcover978-1-4684-5540-3
isbn_ebook978-1-4684-5538-0
copyrightSpringer Science+Business Media New York 1988
The information of publication is updating

书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy影响因子(影响力)




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy影响因子(影响力)学科排名




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy网络公开度




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy网络公开度学科排名




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy被引频次




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy被引频次学科排名




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy年度引用




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy年度引用学科排名




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy读者反馈




书目名称Radiolabeled Monoclonal Antibodies for Imaging and Therapy读者反馈学科排名




单选投票, 共有 1 人参与投票
 

1票 100.00%

Perfect with Aesthetics

 

0票 0.00%

Better Implies Difficulty

 

0票 0.00%

Good and Satisfactory

 

0票 0.00%

Adverse Performance

 

0票 0.00%

Disdainful Garbage

您所在的用户组没有投票权限
发表于 2025-3-21 23:12:31 | 显示全部楼层
Immunochemistry of Hybridomaseasibility of manipulation for specific purposes. Their use, however, is limited because of structural and physicochemical idiosyncrasies, occasionally restrictive factors influencing affinity and avidity, unique cross-reactivities, lack of multivalency compared to polyclonal antibodies, and restric
发表于 2025-3-22 03:10:29 | 显示全部楼层
Characterization and Selection Criteria of Monoclonal Antibodies for Tumor Imaging Studiese the result of alterations in the gene regulation mechanism leading to either a blockage, stimulation or neosynthesis of cell surface molecules which, under normal conditions, would mediate cell-cell interaction and cellular differentiation (1,2). Thus, cells which have been oncologically transform
发表于 2025-3-22 05:57:58 | 显示全部楼层
发表于 2025-3-22 11:48:43 | 显示全部楼层
发表于 2025-3-22 15:15:00 | 显示全部楼层
Selection and Utilization of Monoclonal Antibody Defined Melanoma Associated Antigens for Immunoscinrmation of melanocytes (for review, see 1,2). These antigens are referred to as melanoma associated antigens (MAA). Most of them, if not all of them, are detectable in melanocytes which are cultured . and are likely to be differentiation antigens.
发表于 2025-3-22 19:29:39 | 显示全部楼层
Development and Characterization of Human Monoclonal Antibodies and Their Application in the Radioimse. Antibodies labeled with radioactive isotopes have been demonstrated to localize in tumors of the gastrointestinal tract (1–6), ovary (6), breast (6,7), and skin (8) and promise to be very helpful in identifying metastases in patients with these tumors. However, there remain several problems to b
发表于 2025-3-23 00:21:58 | 显示全部楼层
Progress in Diagnostic Immunoscintigraphy and First Approach to Radioimmunotherapy of Colon Carcinomes injected into a tumor bearing animal can localize preferentially into the tumor, which could be detected by external scanning. These early studies, however, were performed with poorly characterized antibodies obtained by absorption and elution from tumor cells or crude tumor fractions. Thus, this
发表于 2025-3-23 01:36:24 | 显示全部楼层
The Design of a Radiolabeled Monoclonal Antibody for Radioimmunodiagnosis and Radioimmunotherapyridoma technology can be used to discriminate small epitopes on products of either normal or abnormal cells and to produce antibodies which react uniquely with those epitopes, a new generation of biologic targets are being sought on hormones, hormone precursors, myosin, fibrin, blood cells, infectio
发表于 2025-3-23 06:39:33 | 显示全部楼层
Immunohistochemistry and Correlation with Plasma Levels of CA 19-9 and CEA in Gastrointestinal Tumorn and follow-up of malignant tumors has grown steadily (1). The antigenic determinant most likely resides in the peptide portion of the molecule. The specificity of CEA however, is influenced and diminished by various other glycoprotein antigens cross reacting with antisera to CEA. Utilizing hybrido
 关于派博传思  派博传思旗下网站  友情链接
派博传思介绍 公司地理位置 论文服务流程 影响因子官网 SITEMAP 大讲堂 北京大学 Oxford Uni. Harvard Uni.
发展历史沿革 期刊点评 投稿经验总结 SCIENCEGARD IMPACTFACTOR 派博系数 清华大学 Yale Uni. Stanford Uni.
|Archiver|手机版|小黑屋| 派博传思国际 ( 京公网安备110108008328) GMT+8, 2025-5-15 02:40
Copyright © 2001-2015 派博传思   京公网安备110108008328 版权所有 All rights reserved
快速回复 返回顶部 返回列表