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Titlebook: Oxidative Stress, Cell Activation and Viral Infection; C. Pasquier,R. Y. Olivier,Lester Packer Book 1994 Birkhäuser Verlag 1994 AIDS.Activ

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Oxidative Stress and Growth Factor-Mediated Signal Transduction,ve been associated with the control of cellular proliferation, differentiation and transformation. Enhanced protein tyrosine phosphorylation is essential to the stimulation of cell proliferation by peptide growth factors. Growth factors bind to their specific receptors which contain protein tyrosine
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Cellularly generated active oxygen species as signals in the activation of tumour cell growth,ell types when added exogenously. It is also evident that these active oxygen species are released from, or generated within, most of these cell types. Whereas ‘normal’ cells appear to require the stimulus of serum factors or phorbol esters, tumour cells seem to release superoxide constitutively. Ex
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Effect of oxygen radicals on the IL-1 production by monocytes and IL-2 receptor expression in lymph vitro experiments. The effects of oxygen radicals on the producion and reception of IL-1 were evaluated by the addition of antioxidant enzymes, SOD and catalase, and the bioflavonoid rutin, a free radical scavenger and an iron chelator in culture medium. It was found that primary and secondary immu
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The effect of reactive oxygen species (ROS) on human T and B lymphoid cells,ffects of various forms of radiation. These effects may be characteristic of DNA repair capacity and/or intracellular antioxidant levels. In a more physiologically-relevant situation T-lymphoid (Molt-3) cells have been shown to exhibit enhanced susceptibility to H.O.-induced cytogenetic damage and t
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Leukocyte Adhesion and Endothelial Cytokine Production in Hypoxia /Reoxygenation,sion of human resting neutrophils to monolayers with two peaks after 20 min and 4h reoxygenation. This was correlated with the respective expression of the preformed granule membrane protein 140 (GMP-140) and of the . synthesized endothelial leukocyte adhesion molecule 1 (ELAM-1) on endothelial surf
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Effects of Antioxidants on IL-6 Secretion Induced by IL-1 in Human Cultured Lung Fibroblasts. Involendent manner. The transcriptional factor NFκB has been claimed to be involved in the expression of the IL-6 gene after IL-1 stimulation and its activation could be mediated, at least partially, by free radicals produced as second messengers in response to the IL-1 signal. So, we first checked if th
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The Antioxidant Effects of Glutathione and Ascorbic Acid,ne deficiency, induced by administration of buthionine sulfoximine (an inhibitor of the first step of glutathione synthesis) leads to mortality in newborn rats and in guinea pigs, animals that are unable to synthesize ascorbic acid, and to tissue damage in these animals and in adult mice, which can
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,d-α-Tocopherol and Cell Proliferation,lines, such as CHO, osteosarcoma and macrophages are not sensitive. The inhibition depends on the signalling path employed by cells to control proliferation. PDGF-BB is the most d-α-tocopherol sensitive mitogenic stimulus while lysophosphatidic acid is the least. d-β-Tocopherol, an analogue of d-α-t
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