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Titlebook: Oxidative Stress, Cell Activation and Viral Infection; C. Pasquier,R. Y. Olivier,Lester Packer Book 1994 Birkhäuser Verlag 1994 AIDS.Activ

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发表于 2025-3-21 16:34:17 | 显示全部楼层 |阅读模式
书目名称Oxidative Stress, Cell Activation and Viral Infection
编辑C. Pasquier,R. Y. Olivier,Lester Packer
视频video
丛书名称Molecular and Cell Biology Updates
图书封面Titlebook: Oxidative Stress, Cell Activation and Viral Infection;  C. Pasquier,R. Y. Olivier,Lester Packer Book 1994 Birkhäuser Verlag 1994 AIDS.Activ
描述Since the appearance of photosynthesis on our planet, all living organisms have been facing a new abundant, extremely reactive element, oxygen. This element is used for the synthesis of highly energetic compounds, but can also generate molecules capable of damaging constituents of living structures, including proteins, nucleic acids and lipids. It is therefore no surprise that all biological organisms have evolved multiple and sophisticated ways to reduce the detrimental effects of oxygen. For cells and tissues of highly organized animals, particularly cells of the immune system, superoxidation products play an important role, via oxidative stress, in activation, inflammation and viral and bacterial infections. We must be grateful to Drs. C. Pasquier, C. Auclair, L. Packer and R. Olivier for having brought together many specialists in an international meeting held in Paris in March 1993, at the Ministry of Research. This book comprises an impressive amount of recent knowledge, a real mine for the reader in this fast developing field of research. Furthermore, we should not forget that this basic research may lead in the future to new therapeutic approaches to the most important path
出版日期Book 1994
关键词AIDS; Activation; bacteria; cell; immune system; nucleic acid; oxidative stress; pathology; protein; proteins
版次1
doihttps://doi.org/10.1007/978-3-0348-7424-3
isbn_softcover978-3-0348-7426-7
isbn_ebook978-3-0348-7424-3
copyrightBirkhäuser Verlag 1994
The information of publication is updating

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发表于 2025-3-21 23:16:56 | 显示全部楼层
en. This element is used for the synthesis of highly energetic compounds, but can also generate molecules capable of damaging constituents of living structures, including proteins, nucleic acids and lipids. It is therefore no surprise that all biological organisms have evolved multiple and sophistic
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Book 1994lement is used for the synthesis of highly energetic compounds, but can also generate molecules capable of damaging constituents of living structures, including proteins, nucleic acids and lipids. It is therefore no surprise that all biological organisms have evolved multiple and sophisticated ways
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DNA Glycosylases Involved in the Repair of Oxidized Bases in ,, of oxidized DNA bases is mostly mediated by three DNA glycosylases. Endonuclease III excises oxidized pyrimidines and the Fpg protein excises oxidized purines. The MutY protein that cooperates with the Fpg protein to repair 8-oxoguanine residues in DNA.
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,d-α-Tocopherol and Cell Proliferation,ocopherol, with similar antioxidant properties, does not inhibit proliferation. Protein kinase C activity is inhibited by d-α-tocopherol but not by d-β-tocopherol, suggesting a central role of this enzyme in the control of cell proliferation by d-α-tocopherol.
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Leukocyte Adhesion and Endothelial Cytokine Production in Hypoxia /Reoxygenation,These results underline the crucial role played by endothelial-derived oxygen free radicals at reoxygenation in leukocyte adhesion and cytokine synthesis, which could lead to amplify the oxidative stress injury. The protection offered by free radical scavengers emphasizes the potential interest of antioxidants in post ischemic vascular disorders.
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