Titlebook: Optimization of Pharmaceutical Processes; Antonios Fytopoulos,Rohit Ramachandran,Panos M. Pa Book 2022 The Editor(s) (if applicable) and T

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Method of Characteristics for the Efficient Simulation of Population Balance Models,nufacturing, which are modeled by population balance models (PBMs), which are described by coupled nonlinear ordinary and hyperbolic partial differential equations. A substantial literature has investigated ways to reduce the computational cost of simulating these equations, to enable their direct i

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Optimization of Tablet Coating,ication ranges from merely masking the bitter taste and odour of active pharmaceutical ingredients to achieving site-specific and rate-specific drug release. The widespread applicability and high expectations by varied coating techniques have required implication of greater efforts for developing co

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Continuous Powder Feeding: Equipment Design and Material Considerations,ss is considered critical as deviations or disturbances in individual feeders may produce compositional variability in the following mixing steps. This variability may then impact downstream unit operations and result in a detrimental change to the quality attributes of the final product. To design

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Ultrasound for Improved Encapsulation and Crystallization with Focus on Pharmaceutical Applicationsation of ultrasound in the area of food and pharmaceutical processing. This chapter offers discussion on the governing mechanisms for the improvement based on the use of ultrasound, different ultrasonic reactor configurations, as well as the selection of operating conditions for the specific applica

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Nonsmooth Modeling for Simulation and Optimization of Continuous Pharmaceutical Manufacturing Procermaceutical process operations. Process intensification of pharmaceuticals production by continuous manufacturing is challenged by short campaigns, due to the low volume of some products. This calls for optimization of the entire dynamic campaign to achieve the highest overall yields, productivity a

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