Titlebook: Optical Tweezers; Methods and Protocol Arne Gennerich Book 2017 Springer Science+Business Media New York 2017 optical tweezers setups.singl

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Probing DNA–DNA Interactions with a Combination of Quadruple-Trap Optical Tweezers and Microfluidicsch interactions, quadruple-trap optical tweezers have been developed. This technique provides an unprecedented degree of control through the ability to independently manipulate two DNA molecules in three dimensions. In this way, discrete regions of different DNA molecules can be brought into contact

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Single-Molecule Protein Folding Experiments Using High-Precision Optical Tweezers manipulation based on high-resolution optical tweezers (OT) provides a powerful approach to study protein folding with unprecedented spatiotemporal resolution. In this method, a single protein or protein complex is tethered between two beads confined in optical traps and pulled. Protein unfolding i

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Observing Single RNA Polymerase Molecules Down to Base-Pair Resolutiontical trapping assays permit the progress of single molecules of RNA polymerase to be monitored in real time, at resolutions down to the level of individual base pairs. Additionally, optical trapping assays permit the application of exquisitely controlled, external forces on RNAP. Responses to such

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Rafael S. Dutra,Nathan B. Viana,Paulo A. Maia Neto,H. Moysés Nussenzveig