Titlebook: Oncolytic Viruses; Christine E. Engeland Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Virotherapy.Vector D

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A Functional Assay to Determine the Capacity of Oncolytic Viruses to Induce Immunogenic Tumor Cell induce an antitumor immune response. Here, we describe a method to determine if an OV is able to induce such an immunogenic tumor cell death. This method consists in testing whether tumor cells lysed by an OV are able to induce the maturation of human monocyte-derived immature dendritic cells (Mo-iD

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Design and Production of Newcastle Disease Virus for Intratumoral Immunomodulation,important pathogen in the poultry industry. The establishment of a reverse genetics system for this virus has enabled the development of genetically modified recombinant NDV viruses with improved oncolytic and immunotherapeutic properties. In this chapter, we describe the materials and methods invol

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Analysis of Immunological Treatment Effects of Virotherapy in Tumor Tissue,o their immune-stimulatory effects. The shifting focus on virus-mediated immune modulation calls for a comprehensive analysis of the tumor microenvironment (TME) and the factors orchestrating the antiviral and antitumor immune response. The oncolytic VSV-GP studied in our lab is a safe and potent an

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Evaluation of Oncolytic Virus-Induced Therapeutic Tumor Vaccination Effects in Murine Tumor Models,that immunostimulatory properties of oncolytic viruses (OVs) are crucial for their therapeutic efficacy. The specific lysis of tumor cells and release of tumor associated antigens in the context of an OV infection ensures activation of a tumor-specific immune response. The evidence for induction of

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Delivery of Oncolytic Reovirus by Cell Carriers,tment options. However, as single agents oncolytic viruses have shown only moderate clinical benefit and many challenges remain before their full potential is realized. Central to this is the efficient delivery of the virus to the tumor site and potentiation of the antitumor immune response. This ch

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晚来的提名

lymphoma