Titlebook: Oncolytic Viruses; Christine E. Engeland Book 2020 Springer Science+Business Media, LLC, part of Springer Nature 2020 Virotherapy.Vector D

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Eleanor M. Scott,Sally Frost,Hena Khalique,Joshua D. Freedman,Len W. Seymour,Janet Lei-Rossmannd unvermeidbaren Begleiterscheinungen des Straßenverkehrs, sondern überwiegend Folge menschlichen Fehlverhaltens. Unfallchirurgen haben heute neben der Behandlung von Verletzungen und der Rehabilitation der Unfallopfer vermehrt die Verantwortung für die Erarbeitung von Präventionsmaßnahmen...Die Unf

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Brian A. Keller,Marie-Ève Wedge,Abera Surendran,Carolina S. Ilkowd unvermeidbaren Begleiterscheinungen des Straßenverkehrs, sondern überwiegend Folge menschlichen Fehlverhaltens. Unfallchirurgen haben heute neben der Behandlung von Verletzungen und der Rehabilitation der Unfallopfer vermehrt die Verantwortung für die Erarbeitung von Präventionsmaßnahmen...Die Unf

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Introduction to Oncolytic Virotherapy,nment and in situ vaccination effects. Diverse virus platforms have been developed as oncolytic vectors and designed for improved tumor specificity, intratumoral spread, therapeutic gene delivery and especially as targeted cancer immunotherapeutics. This chapter provides a concise overview of the ba

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Tumor Targeting of Oncolytic Adenoviruses Using Bispecific Adapter Proteins,tive delivery to the tumor by systemic administration remains challenging. Several strategies of molecular retargeting have been pursued to equip adenoviruses with molecular features that facilitate their efficient uptake by tumors and to protect healthy tissue from damage. Transductional retargetin

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Ex Vivo Virotherapy with Myxoma Virus to Treat Cancer,ly for European rabbits (.), in which this virus causes the lethal systemic disease called myxomatosis. Importantly, although MYXV cannot cause any disease pathology in humans, mice, or any other domestic animals other than rabbit, this virus can productively infect and kill a variety of human and m

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Immunomodulation in Oncolytic Measles Virotherapy,into focus. The role of the immune system in oncolytic virotherapy is somewhat ambiguous: While preexisting or arising immunity directed against viral antigens may preclude efficient viral replication and spread, immunity directed against tumor antigens is considered essential for long-term treatmen