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Titlebook: Oncogenes; An Introduction to t Kathy B. Burck,Edison T. Liu,James W. Larrick Book 1988 Springer-Verlag New York Inc. 1988 Chromosom.DNA.ca

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书目名称Oncogenes
副标题An Introduction to t
编辑Kathy B. Burck,Edison T. Liu,James W. Larrick
视频video
图书封面Titlebook: Oncogenes; An Introduction to t Kathy B. Burck,Edison T. Liu,James W. Larrick Book 1988 Springer-Verlag New York Inc. 1988 Chromosom.DNA.ca
描述"Cancer viruses" have played a paradoxical role in the history of cancer research. Discovered in 1911 by Peyton Rous (1) at the Rockefeller Institute, they were largely ignored for several decades. Witness his eventual recognition for a Nobel Prize, but not until 1966-setting an all time record for latency, and testimony to one more advantage of longevity. In the 1950s, another Rockefeller Nobelist, Wendell Stanley, spearheaded a campaign to focus attention on viruses as etiological agents in cancer, his plat­ form having been the chemical characterization of the tobacco mosaic virus as a pure protein-correction, ribonucleoprotein-in 1935 (2). This doctrine was a centerpiece of the U.S. National Cancer Crusade of 1971: if human cancers were caused by viruses, the central task was to isolate them and prepare vaccines for immunization. At that point, many observers felt that perhaps too much attention was being devoted to cancer viruses. It was problematic whether viruses played an etiological role in more than a handful of human cancers.
出版日期Book 1988
关键词Chromosom; DNA; cancer; cell; gene; genes; immunodeficiency; leukemia; molecular biology; mutation; oncogene; t
版次1
doihttps://doi.org/10.1007/978-1-4612-3718-1
isbn_softcover978-0-387-96423-2
isbn_ebook978-1-4612-3718-1
copyrightSpringer-Verlag New York Inc. 1988
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Viruses and Oncogenes,th animal and human neoplasia. DNA tumor viruses associated with cancer on epidemiological grounds include papilloma viruses and urogenital cancer, herpes viruses and Burkitt’s lymphoma and nasopharyngeal carcinoma, and hepatitis viruses and liver cancer. No biochemically defined oncogenes have yet
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Cellular Proto-oncogenes,lignant cells were homologous to retroviral oncogenes was made in 1976. Cellular proto-oncogenes have exon and intron structures typical of eukaryotic genes. Some exon sequences are well conserved among vertebrate and invertebrate species. The retroviral life cycle suggests a mechanism whereby cellu
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Oncogenes and Human Cancers,h a variety of mechanisms, have been associated with human cancers. Perturbations in the structure or expression of certain proto-oncogenes appear to be the general means by which this activation occurs..Examples of structural changes are seen in single amino acid substitutions in the . family of ge
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