Titlebook: Oncogene-Directed Therapies; Janusz Rak Book 2003 Springer Science+Business Media New York 2003 angiogenesis.cell.gene therapy.metastasis.

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Targeting Oncogenes in Hematopoietic Malignancieslogy of leukemia was poorly understood. While cytotoxic chemotherapeutic drugs have played, and continue to play, an essential role in cancer management, their relative lack of specificity and the frequency of resistance have been a limit to this approach. This has prompted a search for targeted the

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Clinical Evaluation of Agents Targeting Epidermal Growth Factor Receptor (EGFR) in Cancerrises from a multistep process promoted by the imbalanced growth signals as a consequence of gain of oncogene and/or loss of tumor suppressor genes .. The six essential cancer hallmarks include persistent cell growth signals, insensitivity to antigrowth signals, evasion of apoptosis, persistent angi

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Inhibition of the HER-2/neu Oncogenembers include the epidermal growth factor receptor (EGFR), HER-3, and HER-4 .. The HER-2/neu receptor protein is expressed in a wide variety of tissues, including the breast, ovary, endometrium, lung, liver, gastrointestinal tract, kidney, and central nervous system, and HER-2/neu is believed to pla

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ons in the pancreatic gland of asymptomatic patients, and in the last decades a more detailed and specific pathological classification definitivelyopened an unexpected world of more or less rare pancreatic tumors. As a matter of fact, nowadays most surgical procedures deal with these so called uncom

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Susan J. Done MA, MB, BCHIR, PhD, FRCPC,Jeremy A. Squire PhDons in the pancreatic gland of asymptomatic patients, and in the last decades a more detailed and specific pathological classification definitivelyopened an unexpected world of more or less rare pancreatic tumors. As a matter of fact, nowadays most surgical procedures deal with these so called uncom

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cordingly, it starts with the symptoms and the clinical picture, before addressing the use of radiological and endoscopic studies that are performed to make a diagnosis, and the role of the pathological examination. The book also includes detailed information on the medical treatment of the disease,

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