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Titlebook: Oncogene-Directed Therapies; Janusz Rak Book 2003 Springer Science+Business Media New York 2003 angiogenesis.cell.gene therapy.metastasis.

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发表于 2025-3-21 19:19:05 | 显示全部楼层 |阅读模式
书目名称Oncogene-Directed Therapies
编辑Janusz Rak
视频video
概述Includes supplementary material:
丛书名称Cancer Drug Discovery and Development
图书封面Titlebook: Oncogene-Directed Therapies;  Janusz Rak Book 2003 Springer Science+Business Media New York 2003 angiogenesis.cell.gene therapy.metastasis.
描述Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy.
出版日期Book 2003
关键词angiogenesis; cell; gene therapy; metastasis; oncogene; tumor; tumorigenesis
版次1
doihttps://doi.org/10.1007/978-1-59259-313-2
isbn_softcover978-1-4684-9738-0
isbn_ebook978-1-59259-313-2Series ISSN 2196-9906 Series E-ISSN 2196-9914
issn_series 2196-9906
copyrightSpringer Science+Business Media New York 2003
The information of publication is updating

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The Molecular Basis of Chromosomal Instability in Human Cancer Cellskpoint genes that affect their ability to direct the appropriate segregation of chromosomes in cell division. Future work is aimed at the identification of the genes involved in these processes that are altered in human cancers.
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Oncogenes as Therapeutic Targets to Prevent Metastasis of metastasis affected by Ras suggest that the ability of cancer cells to grow in a secondary site can be significantly affected by activated Ras-signaling. Because oncogene expression can markedly influence the growth phase of the metastatic process, inhibition of oncogene action offers a clinical
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Clinical Evaluation of Agents Targeting Epidermal Growth Factor Receptor (EGFR) in Cancertosis, and inhibition of tumor invasion and metastasis .. Furthermore, overexpression of EGFR, frequently observed in a number of human cancers, is associated with poor overall prognosis, increased tumor recurrence, and decreased patient survival .. The hypothesis that EGFR might be a cancer therape
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