书目名称 | Oncogene-Directed Therapies | 编辑 | Janusz Rak | 视频video | | 概述 | Includes supplementary material: | 丛书名称 | Cancer Drug Discovery and Development | 图书封面 |  | 描述 | Prominent investigators and clinicians summarize in a balanced blend of fundamental science, basic research, experimental therapeutics, and early clinical experiences, what is known about oncogenes and oncogenesis, and describe how that knowledge can be used to treat the cancer. The contributors explain how, why, and under what conditions certain proteins acquire the ability to transform eukaryotic cells, and detail the crucial biological consequences of this oncogenic transformation, particularly for cellular mitogenesis, survival, differentiation, migration, proteolysis, or angiogenic competence. Their articles thoroughly explicate the premises, principles, techniques, and approaches to oncogene targeting in various types of human cancer by using signal transduction inhibitors, immunological targeting methods, and antisense gene therapy. | 出版日期 | Book 2003 | 关键词 | angiogenesis; cell; gene therapy; metastasis; oncogene; tumor; tumorigenesis | 版次 | 1 | doi | https://doi.org/10.1007/978-1-59259-313-2 | isbn_softcover | 978-1-4684-9738-0 | isbn_ebook | 978-1-59259-313-2Series ISSN 2196-9906 Series E-ISSN 2196-9914 | issn_series | 2196-9906 | copyright | Springer Science+Business Media New York 2003 |
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