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Titlebook: OCT and Imaging in Central Nervous System Diseases; The Eye as a Window Andrzej Grzybowski,Piero Barboni Book 20202nd edition Springer Nat

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Seeing the Brain Through the Eye: What Is Next for Neuroimaging and Neurology Applications,odegenerative disorders..In this chapter, we will give an overview of Optical Coherence Tomography as an emerging technology in neurology applications and express our view about how retinal imaging could serve the above goals and open a window, which could serve as a direct view to the brain.
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Advances in Retinal Imaging: Real-Time Imaging of Single Neuronal Cell Apoptosis (DARC),rmation on disease progression of neurodegeneration both in glaucoma and CNS conditions such as Alzheimer’s disease, where apoptosis is thought to play a key role. The ability of DARC to predict future progression would therefore lend itself as an invaluable surrogate marker in clinical trials, expe
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OCT and Multiple Sclerosis,such as magnetic resonance imaging (MRI), electrophysiology, visual acuity, and disability rating scales. Emerging themes within the topic, such as the proposed importance of the macular inner nuclear layer (INL) and the recent development of OCT angiography (OCT-A), are introduced. Finally, we summ
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,Optical Coherence Tomography in Alzheimer’s Disease,d to neuronal degeneration in the ganglion cell layer and not to a retrograde degeneration from changes in the post-chiasmatic visual pathway. These data suggest a possible role of OCT in monitoring the progression of AD and in assessing the effectiveness of purported AD treatments.
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Hereditary Optic Neuropathies,he optic nerve head (ONH) reveals that larger optic discs are associated with a better prognosis..In DOA, the RNFL and GCL analysis reveals diffuse atrophy in all the sectors. The RNFL thinning is more pronounced in the temporal and inferior quadrants and less evident in the superior and nasal ones.
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Animal Models in Neuro Ophthalmology,re still suboptimal for human neuro-ophthalmic conditions because of anatomical differences between species. Primate models have the obvious advantage of sharing vast anatomical and genomic similarities with humans. However, monkeys are expensive, difficult to breed and can only be handled by qualif
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Andrzej Grzybowski,Piero BarboniBroadens understanding of OCT imaging and interpretation in clinical practice.Discusses the role of OCT in evaluating disease progression in neurodegenerative disorders.Presents translational aspects
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