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Titlebook: Nutrition and Biotechnology in Heart Disease and Cancer; John B. Longenecker,David Kritchevsky,Marc K. Drez Book 1995 The Editor(s) (if ap

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Historical Review of Research on Atherosclerosisnd they have their own research histories, but it is the history of the underlying atherosclerosis or hardening of the arteries about which I shall speak. I have listed several sources for this paper and they have extensive bibliographies for specific points of reference.
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Nutrition and Coronary Heart Disease Epidemiologye evolved with recognition of the importance of many risk factors. However, despite acceptance of the concept of multifactorial causality, and continuing identification of an increasingly larger number of contributing factors extending from the molecular genetic to the societal level, the role of nu
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Obesity, Fat Patterning and Cardiovascular Riskpast 10 to 15 years. The concept of an “apple shaped” body being associated with higher risk than a “pear shaped” body has appeared in the lay literature, and as a result, questions concerning fat distribution are being directed to physicians and other health care professionals. The purpose of this
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Role of Oxidized LDL and Antioxidants in Atherosclerosisin the form of myocardial infarction, stroke and peripheral vascular disease accounts for about 50% of all deaths in developed countries. It is a disease of aging, in the sense that the occurrence of clinically significant lesions increases sharply past the 5th decade, but it is equally clear that c
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Signal Transduction in Atherosclerosis: Second Messengers and Regulation of Cellular Cholesterol Traremain undefined. Prior to the 1970’s, the prevailing view of atherogenesis was the concept that lipid infiltration from plasma-derived LDL was necessary and sufficient to elicit an atherogenic response. However, a fresh and intriguing view was proposed by Ross and Glomset in 1976. They suggested th
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Gene Therapy in Heart Diseaseally aimed at symptoms or secondary defects and almost never at the precise biochemical or genetic disease itself. The ideal treatment could involve actual change or replacement of defective genes (Friedman, 1983). In spite of remarkable surgical and pharmaceutical advances, therapy of the more than
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Impact of Biotechnology in the Diagnostic and Therapeutic Management of Cardiovascular Disorders (t-PA), urokinase, platelet targeting antibodies, recombinant anticoagulant agents such as hirudin and various modulatory proteins. On the diagnostic front, biotechnology has provided newer, more sensitive methods to detect minute changes in blood for the proper diagnosis and management of cardiova
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