Titlebook: Nucleic Acid Crystallography; Methods and Protocol Eric Ennifar Book 2016 Springer Science+Business Media New York 2016 DNA.Macromolecule P

高射炮

Preparation and Crystallization of Riboswitchesite-sensing segments of mRNAs called riboswitches are unique. Discovered over a decade ago in all three kingdoms of life, riboswitches specifically and directly interact with various metabolites and regulate expression of multiple genes, often associated with metabolism and transport of small molecu

小歌剧

影响带来

万神殿

Verify

Radiculopathy

Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes a considerable portion of the total number of oligo-2′-deoxynucleotide structures determined over the last 30 years. The dodecamer has commonly served as a template to analyze the effects of sequence on DNA conformation, the conformational properties of chemically modified nucleotides, DNA–ligand i

Bernstein-test

Isothermal Titration Calorimetry: Assisted Crystallization of RNA–Ligand Complexesble biophysical approaches, isothermal titration calorimetry (ITC) is certainly a method of choice. ITC can be used in a wide range of experimental conditions to monitor in real time the formation of the RNA– or DNA–ligand complex, with the advantage of providing in addition the complete binding pro

Mosaic

BATE

Advanced Crystallographic Data Collection Protocols for Experimental Phasingucture determination. Continuous advances at third-generation synchrotron sources have enabled the deployment of rapid data collection protocols that are capable of recording SAD or MAD data sets. However, procedural simplifications driven by the pursuit of high throughput have led to a loss of soph

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Nucleic Acid Crystallography via Direct Selenium Derivatization: RNAs Modified with Se-Nucleobasesum modifications, researchers can determine novel RNA structures via convenient SAD and MAD phasing. As one of the naturally occurring tRNA modifications, 2-seleno-uridine, which presents almost exclusively at the wobble position of anticodon loop in various bacterial tRNAs (Ching et al., Proc Natl