书目名称 | Nucleic Acid Crystallography | 副标题 | Methods and Protocol | 编辑 | Eric Ennifar | 视频video | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | .This volume includes comprehensive and up-to-date coverage of all nucleic-acid-specific steps used in X-ray crystallography, from macromolecule production to structure determination. Chapters dedicated to RNA preparation and crystallogenesis will be of interest to beginners, while chapters focused on data collection, phasing and refinement will be particularly useful to researchers with a higher level of expertise. Several functional case studies are also presented in the last part of the book. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and thorough, .Nucleic Acid Crystallography: Methods and Protocols. presents protocols that are aimed at both researchers and students who are interested in the structural biology of DNA or RNA, alone or in complex with proteins or ligands.. | 出版日期 | Book 2016 | 关键词 | DNA; Macromolecule Production; Nucleic Acid Crystallography; Nucleic Acid Purification; Nucleic Acid Syn | 版次 | 1 | doi | https://doi.org/10.1007/978-1-4939-2763-0 | isbn_softcover | 978-1-4939-4641-9 | isbn_ebook | 978-1-4939-2763-0Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media New York 2016 |
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