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Titlebook: Nuclear Imaging in Drug Discovery, Development, and Approval; H. Donald Burns,Raymond E. Gibson,Peter K. S. Sieg Book 1993 Birkhäuser Bost

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The Role of Positron Emission Tomography in Assessing and Monitoring Dopamine Active Drugs,ders. The dopaminergic system is one of the most commonly implicated neuroreceptor neurotransmitter systems. Diseases such as Tourette’s Syndrome, schizophrenia, and Parkinson’s Disease are examples of such disorders where dopamine is suspected of playing an important role. Positron Emission Tomogra
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Iodinated Dopamine D1 and D2 Receptor Imaging Agents for SPECT,ntral nervous system (CNS) very important for normal brain function, it is also a possible primary action site for antiparkinsonian agents or neuroleptic drugs for schizophrenia. Addiction to cocaine, which is an acute social and economic problem, is related to the CNS reward system involving dopami
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Radiolabeled Atrial Natriuretic Peptide and Somatostatin for , Imaging of Receptors,ors. Such methods provide microscopic information on a cellular level but little overall information about the . biodistribution of the receptors and their dynamic relationship with their endogenous ligands. The gathering of this . information by techniques such as Nuclear Imaging has been limited b
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Use of Radionuclides in Experimental Vascular Thrombosis,e world (Collen and Gold, 1990). Arterial high shear conditions promote the formation of thrombus composed primarily of platelets, while low shear venous conditions promote the formation of thrombus composed primarily of fibrin and red blood cells (Cadroy and Harker, 1990). The critical role of plat
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The Gastrointestinal Transit and Systemic Absorption of Diltiazem HCL from a Modified Release Dosag provide a rapid disintegration in the stomach, however, over the last 5–6 years there has been a growing trend within the pharmaceutical industry to develop complex pharmaceutical dosage forms designed to deliver drug in a controlled or timed released manner after oral administration. The design of
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Leslie Lars Iversenthe evidence is very recent and for the first time all this archaeobotanical evidence is brought together in one volume (at present the information is unpublished or published in many disparate journals, confer­ ence reports, monographs, site reports, etc. ). Early publications concerned with the or
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