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Titlebook: Nuclear Imaging in Drug Discovery, Development, and Approval; H. Donald Burns,Raymond E. Gibson,Peter K. S. Sieg Book 1993 Birkhäuser Bost

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发表于 2025-3-21 19:11:54 | 显示全部楼层 |阅读模式
书目名称Nuclear Imaging in Drug Discovery, Development, and Approval
编辑H. Donald Burns,Raymond E. Gibson,Peter K. S. Sieg
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图书封面Titlebook: Nuclear Imaging in Drug Discovery, Development, and Approval;  H. Donald Burns,Raymond E. Gibson,Peter K. S. Sieg Book 1993 Birkhäuser Bost
描述It is the purpose and business of the pharmaceutical industry to dis­ cover, develop, and make available drugs for the care of the sick. The purpose of universities and national laboratories is to provide people and scientific knowledge that can help in the process. This book presents the combined efforts of scientists from the drug in­ dustry, academic laboratories and national laboratories to describe advances in radiotracer technology in studies on experimental ani­ mals and living human beings. The authors believe that the technol­ ogy is now ready for widespread application in the pharmaceutical industry. The goal of this book is to help bring this about. The field of Nuclear Medicine is based on the concept that, if treatment of disease is chemical, the patient‘s diagnosis should be chemical. Anatomy and histopathology have been the principle ba­ sis for making a diagnosis. Histopathologic data suffer from being descriptive, subjective, not quantifiable, and based on the study of dead tissue. The era of histopathology as the dominant concept in medical practice is coming to an end. Histopathologic findings are often heterogeneous and a single biopsy will at times not reveal t
出版日期Book 1993
关键词anatomy; chemistry; drug discovery; drug research; drugs; evaluation; experiment; medicine; nature; pharmaceu
版次1
doihttps://doi.org/10.1007/978-1-4684-6808-3
isbn_softcover978-1-4684-6810-6
isbn_ebook978-1-4684-6808-3
copyrightBirkhäuser Boston 1993
The information of publication is updating

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发表于 2025-3-21 21:00:06 | 显示全部楼层
Nuclear Medicine Physics, Instrumentation, and Data Processing in Pharmaceutical Research,ined from such studies, an appreciation of basic nuclear medicine physics, instrumentation, and data processing is required. The techniques to be considered here include both planar and tomographic imaging, the latter including both Single Photon Emission Computed Tomography (SPECT) and Positron Emi
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Accelerators for Positron Emission Tomography,rement is for these accelerators to deliver particle beams of sufficient energy to bring about the required nuclear reactions and with sufficient beam current to bring about practical yields of the required radionuclides. Table 1 lists the positron emitters, their characteristics and the most common
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Chemistry of Tracers for Positron Emission Tomography,mited number, a select few have been used to study biochemistry and pharmacology . with emission tomography. Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) offer biomedical researchers unique opportunities for studying a wide variety of biochemical and phar
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Single Photon, Gamma Emitting Radiotracers for Use in Imaging,isotopically labeled compounds (primarily Carbon-11 or Fluorine-18) and Positron Emission Tomography (PET) imaging to obtain information on drug absorption, distribution, metabolism and elimination. Imaging studies in humans with these labeled drugs or drug candidates can be used to compliment infor
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Applications of Autoradiography to Drug Discovery,atures which define the usefulness of Nuclear Medicine in drug discovery are applicable to autoradiographic techniques. Additionally, autoradiographic studies, both . and ., have been used to characterize the properties of radiolabeled drugs used in nuclear medicine (Huang and Phelps, 1986; Kung et
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Positron Emission Tomography, Enzymes and Drug Research and Development,havioral, therapeutic and toxic properties of drugs is emerging as a powerful new scientific tool (Fowler et al., 1990). PET provides a new perspective on drug research by virtue of its ability to directly assess different parameters such as absolute uptake, regional distribution, kinetics, pharmaco
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