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Titlebook: Nuclear Imaging in Drug Discovery, Development, and Approval; H. Donald Burns,Raymond E. Gibson,Peter K. S. Sieg Book 1993 Birkhäuser Bost

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Use of Radionuclides in Experimental Vascular Thrombosis,litate study of the effects of pharmacological intervention on experimental thrombosis. In this chapter, we describe the systemic application of nuclear medicine technology to assess the antithrombotic efficacy of putative therapeutic agents in a baboon model of platelet-dependent vascular graft thrombosis.
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Application of Nuclear Imaging to Drug Delivery Evaluation and Development: A Review of Radiolabeleelop formulations of lipid soluble drugs which are not very soluble in aqueous solutions. Of particular interest are micro and nanocolloidal particles, liposomes, fat emulsions, and microfine emulsions.
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Single Photon, Gamma Emitting Radiotracers for Use in Imaging,the drug in other tissues (suggesting potential toxic side effects in that tissue). They can also be used to evaluate the effect that factors such as formulation and route of administration, have on the biodistribution of a drug. This type of study, however, is limited to the use of short-lived, pos
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