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Titlebook: Novel Inhibitors of Leukotrienes; Giancarlo Folco,Bengt Samuelsson,Robert C. Murphy Book 1999 Springer Basel AG 1999 asthma.cell.developme

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Physiological and pathophysiological activities of leukotrienes,rest turned also to other tissues and organ systems, with the ultimate goal of disclosing specific targets for the different LTs. It is now generally accepted that the LTs collectively provoke contraction of vascular and nonvascular smooth muscle, increased vascular permeability, and accumulation an
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Genetic polymorphisms of 5-LO,hat 5-LO products contribute to a variable extent in the overall pathogenesis of asthma. As a result of these differences, patients overexpressing 5-LO, and therefore 5-LO products, will be more responsive to 5-LO inhibition, whereas other patients whose disease is less dependent on 5-LO activity wi
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Leukotrienes in nocturnal asthma,lows. The leukotrienes must (i) be able to cause the symptoms and pathophysiologic changes of nocturnal asthma, (ii) be made by the cells present in the airways of nocturnal asthmatics, (iii) be measured in asthmatics at night during symptoms and correlate with disease severity and (iv) be blocked b
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Sally E. Wenzelll of the new tools available to the service of science, for example:-particle accelerators, magnetic resonance, electron microscopy, lasers - have entered the general arsenal following a period of adaptation. Like them, the rocket is now a classical instrument, and gives information even to those f
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