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Titlebook: Novel Angiogenic Mechanisms; Role of Circulating Nicanor I. Moldovan Book 2003 The Editor(s) (if applicable) and The Author(s), under excl

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Cross Talk between Haematopoiesis and Angiogenesis,ast, gives rise to both cell types in the yolk sac, the initial site of haematopoiesis and of blood vessel formation (.). Generation of haemangioblasts take place from embryonic stem cells (ESC) or from yolk sac blood islands or from intraembryonic AGM (aortagonad-mesonephros) region, containing the
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, Transformation of Monocytes and Dendritic Cells into Endothelial like Cells,te into endothelial-like cells (ELC), which are characterized by the expression of endothelial markers and the formation of tube-like structures. Dependent on the culture conditions a mixed macrophage/endothelial or an endothelial phenotype could be induced. A similar pattern of development could be
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Dissection of Monocyte and Endothelial Activities by Using VEGF-Receptor Specific Ligands,proliferation of endothelial cells but not fibroblasts (.). Based on this competency VEGF emerged as a highly good candidate as an angiogenesis-specific factor. Because VEGF is produced in response to hypoxia it describes a physiological mean to ablate the need of nutrients and oxygen by the inducti
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