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Titlebook: Novel Angiogenic Mechanisms; Role of Circulating Nicanor I. Moldovan Book 2003 The Editor(s) (if applicable) and The Author(s), under excl

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书目名称Novel Angiogenic Mechanisms
副标题Role of Circulating
编辑Nicanor I. Moldovan
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Novel Angiogenic Mechanisms; Role of Circulating  Nicanor I. Moldovan Book 2003 The Editor(s) (if applicable) and The Author(s), under excl
描述New experimental observations often require fresh concepts for their interpretation, and at times even changes of paradigms. This is the situation with the recent realization that circulating endothelial progenitor cells may have an important contribution to the maintenance and formation of new endothelium in adult organisms, in a surprisingly wide variety of situations. The classical paradigm of angiogenesis, centered on the notion of "sprouting" can hardly accommodate them. It was previously realized that it needs to be "stretched out" to include alternative mechanisms of microvascular development, such as intussusception and capillary fusion. However, a major debate where to reconsider the sprouting mechanism, and to promote alternative views, did not take place yet. The number of publications in this field increased exponentially in the last years. Nevertheless, the concepts and notions so much needed to describe and to explain the new observations are still scarce, and heterogeneous. Within the larger community dedicated to the study of angiogenesis, the researchers involved in investigation of circulating precursor endothelial cells biology represent a subgroup with specific
出版日期Book 2003
关键词angiogenesis; cardiovascular; cells; endothelium; tissue
版次1
doihttps://doi.org/10.1007/978-1-4615-0169-5
isbn_softcover978-1-4613-4951-8
isbn_ebook978-1-4615-0169-5Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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, Transformation of Monocytes and Dendritic Cells into Endothelial like Cells,that monocytes are precursors of different subgroups of endothelial cells and that the formation of endothelial cells from CD34. progenitor cells follows a similar pathway possibly via the monocyte and/or the immature dendritic cell.
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The Contribution of Adult Hematopoietic Stem Cells to Retinal Neovascularization,h as pericyte death and subsequent endothelial cell proliferation.. Compensatory neovascularization then results in the formation of aberrant and pathologic capillaries. An important question whose answer would have broad implications for potential therapeutic strategies is the origin of the cells responsible for compensatory neovascularization.
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In Vivo and in Vitro Properties of CD34+ and CD14+ Endothelial Cell Precursors,cells that integrate into the endothelium and function as endothelial cells. A number of years ago Dr. Isner and colleagues were studying the effect of vascular endothelial cell growth factor (VEGF) on reendothelialization of arteries. To test this, they denuded carotid arteries bilaterally and then
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Evidence from a Leukemia Model for Maintenance of Vascular Endothelium by Bone-Marrow-Derived Endotovo by the aggregation of angioblasts, a process that is termed . In postnatal life, the development of new blood vessels is restricted to the female reproductive tract (during the ovulatory cycle) and to sites of wound healing, and occurs through a process called ., i.e. the sprouting of new vessel
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