Titlebook: New Aspects in Regional Anesthesia 4; Major Conduction Blo Hans Joachim Wüst,M. d’Arcy Stanton-Hicks (Profess Conference proceedings 1986 S

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藕床生厌倦

Tachyphylaxis and Local Anestheticsty of nerve blockade, becoming with observable with repeated injections. However, studies of single nerves or nerve fibers in vitro do not show any such effect. Nerve block obtained with a local anesthetic can be reversed and reinstituted almost indefinitely by washing out and rebathing the preparat

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Pharmacologic Regulation of Local Anesthetic Conduction Block by Cyclic AMPe most popular concept suggests that there is a reduction in the amount of free base available for block due to a progressive decrease in local pH. An alternative hypothesis suggests that tachyphylaxis may be due to a true reduction in effect of the local anesthetic at the receptor level. Further pr

Grasping

Panel Discussion: Tachyphylaxis and Local Anestheticsanesthetics were verified by pin prick or by measuring sympathetic activity. In investigating this problem, it is very important to measure pain. Tachyphylaxis has been under discussion for about 13 years. Why has nobody done a prospective randomized study?

Nmda-Receptor

Pathophysiology of Hypotension Induced by Spinal/Epidural Analgesia maintain blood pressure [1]. Imbalance between vasodilatation and vasoconstriction is the most common mechanism underlying hypotension associated with spinal/epidural analgesia and occurs if the block is widespread or in the presence of hypovolemia, even with a limited block [2]. The mechanism for

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Direct Vascular Effects of Some Local Anesthetics: A Mechanical and Electrophysiological Studyferent mechanisms. When analyzing the cardiovascular effects of LA it is necessary to make a basic distinction between their direct effects, which result from systemic administration or from absorption into vessels when they are applied locally, and their indirect effects, which arise from the block

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Subarachnoid Block Spares Visceral Blood Flow and Drug Elimination Capacitylow which may alter the disposition of, or response to, any drugs they may receive [1,2]. There is little information to guide rational therapy, as much of the available information about drug disposition has been obtained using the compartmental method. Although it has proved very useful, this meth

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Severe Hypotension and Major Conduction Anesthesiacerned. One must expect myocardial ischemia as shown by ECG changes in patients with cardio circulatory disease who suffer hypotension lasting longer than 10 min [10]. Likewise, a pressure-dependent, restricted cerebral blood flow might result in serious hypoxic brain injuries. A severe reduction in