Titlebook: New Aspects in Regional Anesthesia 4; Major Conduction Blo Hans Joachim Wüst,M. d’Arcy Stanton-Hicks (Profess Conference proceedings 1986 S

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New Aspects in Regional Anesthesia 4978-3-642-70807-7Series ISSN 0171-1814

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Tachyphylaxis in Regional Anesthesia: Can We Reconcile Clinical Observations and Laboratory Measuremo the blockade of motor neurons may also be observed. To account for these observations, Tucker and Mather [1] proposed that either there is a true reduction in effect at the receptor level or the fraction of dose reaching the receptors decreases with successive injections.

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Tachyphylaxis and Local Anestheticsion with drug, with no apparent evidence of resistance to the action of the drug. Therefore, when increasing resistance to repeated injections occurs clinically, it may be profitable to seek other causes for what may be termed “pseudotachyphylaxis”.

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Severe Hypotension and Major Conduction Anesthesia blood pressure can thus be responsible for grave sequalae [7]. One should be aware of the frequency with which hypotensive reactions occur during different anesthetic procedures in order to take the most effective preventative measures.

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Hemodynamic Effects and Mechanism of Action of Dihydroergotamine in Epidural Anesthesiansatory mechanisms, activated by a decrease in perfusion pressure, may necessitate immediate treatment if the venous return is restricted by a loss of effective blood volume from hemorrhage or by postural pooling in regions of vasodilatation.

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Conference proceedings 1986acks are associated with their use: hypotension during surgery and the development of tolerance in long-term epidural analgesia. When opiates are injected epidurally or intrathecally, numerous side effects such as itching, nausea and vomiting, or respiratory depression have been reported. The pathop

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No Tachyphylaxis with Prolonged, Continuous Bupivacainestoperative pain relief using continuous epidural infusion of lidocaine [4]. They predict that there should be considerable local accumulation without corresponding diminution of the required anesthetic dosage.