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Titlebook: New Aspects in Regional Anesthesia 4; Major Conduction Blo Hans Joachim Wüst,M. d’Arcy Stanton-Hicks (Profess Conference proceedings 1986 S

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Panel Discussion: Tachyphylaxis and Local Anestheticsanesthetics were verified by pin prick or by measuring sympathetic activity. In investigating this problem, it is very important to measure pain. Tachyphylaxis has been under discussion for about 13 years. Why has nobody done a prospective randomized study?
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Direct Vascular Effects of Some Local Anesthetics: A Mechanical and Electrophysiological Studyferent mechanisms. When analyzing the cardiovascular effects of LA it is necessary to make a basic distinction between their direct effects, which result from systemic administration or from absorption into vessels when they are applied locally, and their indirect effects, which arise from the blockade of sympathetic fibers.
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Experimental Tachyphylaxis: Development of a Continuous Epidural Dog ModelThe recognition of tachyphylaxis or acute tolerance to local anesthetics is not universal and depends on a number of factors: the perspective of the observer, the nature of the regional anesthetic, whether the observations are made on the basis of an in vitro or in vivo animal model, and not least, how it is defined.
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Hemodynamic Effects of Different Vasopressors (Etilefrine, Norfenefrine, Akrinor, Amezinium MetilsulThe most prominent effect of a paraspinal anesthetic block on the overall physiologic equilibrium is not the sensory, nociceptive, or motor blockade; of far greater importance is the autonomic denervation with its profound hemodynamic, microcirculatory, and endocrine reactions.
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