书目名称 | Neurotrophic Factors | 编辑 | Franz Hefti | 视频video | | 丛书名称 | Handbook of Experimental Pharmacology | 图书封面 |  | 描述 | The pharmacology of neurotrophic factors is part of the general field called neuroprotection or neurodegeneration, which has emerged during the past two decades. This new broad research area has identified molecular mechanisms that regulate the morphological plasticity of the nervous system and, in con sequence, discovered novel pharmacological approaches to manipulate these processes in disease states. The new, structural neuropharmacology as de scribed in this volume attempts to regulate the anatomic aspects of the nervous system and is perhaps comparable to hardware manipulation in computer systems. In contrast, classical neuropharmacology identified multiple ways to modify the function of existing synapses or ion channels in the nervous system, comparable to software manipulations in the computer field. The pharmacol ogy of neurotrophic factor is at an early stage and has not produced any major drugs yet. However, the first quintessential clinical trials have been carried out in the past two years or are currently in progress. Rapid further advances can be expected. The discovery of nerve growth factor (NGF), the first protein known to promote survival and growth of nerve ce | 出版日期 | Book 1999 | 关键词 | Alzheimer´s disease; anatomy; brain; brain injury; cerebral ischemia; clinical trial; growth factor; mutage | 版次 | 1 | doi | https://doi.org/10.1007/978-3-642-59920-0 | isbn_softcover | 978-3-642-64182-4 | isbn_ebook | 978-3-642-59920-0Series ISSN 0171-2004 Series E-ISSN 1865-0325 | issn_series | 0171-2004 | copyright | Springer-Verlag Berlin Heidelberg 1999 |
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