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Titlebook: Neurotrophic Factors; Franz Hefti Book 1999 Springer-Verlag Berlin Heidelberg 1999 Alzheimer´s disease.anatomy.brain.brain injury.cerebral

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Neurotrophic Factors in Peripheral Nerve Injury and Regeneration,ent pain, respiratory complications, paralysis). Collectively, these conditions represent a major medical challenge because of the spectrum and severity of the resulting disability. Presently, there are few, if any, palliative treatments available and no curative therapy able to halt disease progression or restore normal function.
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,Nerve Growth Factor Treatment for Alzheimer’s Disease: The Experience of the First Attempt at Intraf plaques to the APP fragment, A/β. Since A/β is neurotoxic, at least in vitro, the hypothesis includes the view that neuron loss is secondary to the initial nucleation of neuritic plaques caused by Aβ.
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Biological Roles of Neurotrophins,ave been identified in mice and in humans that encode for small dimeric, secretory proteins named nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3) and neurotrophin-4/5 (NT4/5).
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Molecular Anatomy of Neurotrophic Factors,n than not, neurotrophic factors interact with multi-component receptors consisting of several distinct protein subunits. In some cases, such as the receptor complexes for ciliary neurotrophic factor (CNTF) and glial cell line-derived neurotrophic factor (GDNF), the tasks of ligand binding and downs
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Neurotrophin Treatment of Peripheral Sensory Neuropathies,ents, such as taxol, cisplatin and vincristine; mechanical compression; ischemia; HIV and other viral infections; hereditary causes; and inflammatory and immune diseases. The etiology of some peripheral neuropathies remains obscure, despite thorough evaluations of the known causes; these are classif
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Neuropharmacology of Insulin-Like Growth Factors,es and disorders of the nervous system. The cost of treating trauma and neurodegenerative disorders is staggering. For example, the annual expenditure in the United States for CNS trauma is US $4.7 billion, for stroke $11.3 billion, for Parkinson’s disease and other movement disorders $2.5 billion,
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,Nerve Growth Factor Treatment for Alzheimer’s Disease: The Experience of the First Attempt at Intraeuritic plaques, neurofibrillary tangles and neuron loss in the brain. The discovery of amyloid precursor protein (APP), the genetic analysis of familial forms of AD, and observations on transgenic animals have produced a widely accepted hypothesis which ascribes the central role in the generation o
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