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Titlebook: Neurotransmitters and Drugs; Zygmunt L. Kruk,Christopher J. Pycock Book 1991Latest edition Zygmunt L. Kruk and Christopher J. Pycock 1991

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Neurotransmission: sites at which drugs modify neurotransmission,of the effects of poisons on animals. It was found that some poisons could mimic the effects of stimulating certain nerves, and it must have occurred to somebody that nerves release chemicals in response to stimulation. Histological studies showed that there is always a gap between the nerve ending
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Noradrenaline,stem (CNS). Noradrenaline is released from the adrenal medulla. The term ‘catecholamine’ refers to the chemical classification in which substances with two adjacent hydroxyl (OH) groups on a benzene ring are said to have a ‘catechol’ nucleus.
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5-Hydroxytryptamine,tions are found in the enterochromafin cells in the lining of the alimentary canal and in the blood platelets. 5-HT is released from platelets at sites of tissue injury, and 5-HT in the systemic circulation (plasma) has a wide range of effects on nerve terminals and blood vessels which do not have a
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Histamine,n the stomach. Its functional roles in the CNS are not well established; in the stomach it is an important stimulus for the secretion of hydrochloric acid; its release from mast cells and basophils occurs following allergic reactions and injury. Histamine is an important regulator of repair processe
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Peptides and neuronal function,as substance P (SP), and it is discussed later in this chapter. The observation which was to prove to be of great significance was that the biological activity of substance P could be destroyed by trypsin, thus showing that substance P was a peptide. Some 30 years later, Harris showed that the relea
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978-0-412-36110-4Zygmunt L. Kruk and Christopher J. Pycock 1991
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Croom Helm Biology in Medicine Serieshttp://image.papertrans.cn/n/image/664586.jpg
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https://doi.org/10.1007/978-94-011-3134-6CNS; GABA; dopamine; drug; nervous system; neuropeptides; neurotransmitter; opioid; research
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