Titlebook: Neuropsychiatric Systemic Lupus Erythematosus; Pathogenesis, Clinic Shunsei Hirohata Book 2018 Springer International Publishing AG, part o

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Clinical Features,ood disorders, anxiety disorders and cognitive dysfunction are sometimes mild, and are also common in individuals without SLE. Also, we need to remember that NPSLE can be developed even in the absence of systemic disease activities. Finally, some neuropsychiatric manifestations have not been adequately defined in the ACR nomenclature.

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Imaging of Neuropsychiatric Systemic Lupus Erythematosus, NPSLE. New MRI techniques can give us more detailed information in patients with NPSLE in addition to findings by conventional MRI. Functional analysis of the CNS by imaging system would be promising.

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Immunopathology of Neuropsychiatric Systemic Lupus Erythematosus,sychosis, mood disorders, cognitive dysfunctions and acute confusional state. In the latter process, autoantibodies, such as anti-ribosomal P antibodies, anti-NMDA receptor NR2 antibodies and anti-Sm antibodies, play a pivotal role. Greater attention is now paid to the role of microglia in the pathogenesis.

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Shunsei HirohataEnglish, Spanish, Turkish, and German leagues were the most competitive, respectively. The French and Turkish leagues provided the highest level of efficiency and productivity with minimum spectator, market value, and transfer expenditure. In the model where the HHI and the EI scores were considered