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Titlebook: Neuropsychiatric Dysfunction in Multiple Sclerosis; Ugo Nocentini,Carlo Caltagirone,Gioacchino Tedesch Book 2012 Springer-Verlag Italia 20

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Epidemiologyn; the long-standing statement that MS prevalence and incidence increase with the distance from the equator has been challenged by more recent research; differences in the frequencies of the disease in different populations and races in the same country have been, instead, confirmed. Data coming fro
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Etiopathogenesista suggest that MS is a multifactorial disease in which one or more environmental factors contribute to trigger an immune response directed against myelin antigens in genetically susceptible subjects. From a pathogenic point of view it is important to consider: genetic, viral and immunological facto
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Neuropathologylished that plaques are present not only in the white matter of the brain, cerebellum, brainstem and spinal cord, but also in the gray matter. The introduction of double inversion recovery MRI sequences has made possible to show that cortical lesions are consistently present, not only in patients wi
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Therapy of Multiple Sclerosis available that can efficiently treat relapses, reduce relapse rate and, partially, disability progression, and improve some symptoms. This means that we are able to change the overall course of the disease.
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