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Titlebook: Neuroprotective Signal Transduction; Mark P. Mattson Book 1998 Springer Science+Business Media New York 1998 Deprivation.Nervous System.Pa

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978-1-4757-5968-6Springer Science+Business Media New York 1998
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Contemporary Neurosciencehttp://image.papertrans.cn/n/image/664379.jpg
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Protective and Regenerative Properties of GDNF in the Central Nervous System,t to identify new trophic factors for midbrain dopamine (DA) neurons. Since the initial description of GDNF in 1993, studies from a number of laboratories have confirmed its potent effects on DA neurons. In addition, GDNF has been found to play an intricate role in the survival and development of a diverse set of neuronal and nonneuronal cells.
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Book 1998neration and death of neurons occurring in both acute and chronic neurodegenerative disorders. Authoritative contributions dissect the signaling pathways of an array of neuroprotective factors-ranging from neurotrophins (NGF, BDNF, NT-3, and NT-4/5), to growth factors (bFGF, IGF-1, GDNF), to cytokin
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Neuroprotective Strategies Involving the Neurotrophins and Their Signaling Pathways, by mechanical injury or damaged by neurotoxins (Table 1). These observations have led to the hypothesis that the neurotrophins have therapeutic potential in the treatment of a wide range of insults to the nervous system, including neurodegenerative disorders, peripheral neuropathies, and traumatic injury.
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