Titlebook: Neuroendocrine Molecular Biology; G. Fink,A. J. Harmar,Kenneth W. McKerns Book 1986 Plenum Press, New York 1986 biology.development.endocr

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The Role of Brain Peptides in the Control of Anterior Pituitary Hormone Secretional releasing and inhibiting hormones act directly on the pituitary to inhibit or stimulate the release of anterior pituitary hormones. They appear also to act within the brain to modulate their own release and that of other releasing factors. With the discovery of many additional brain peptides, mos

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The Mammalian Tachykinins and Their Receptors: Structure-Activity Relationship of the Mammalian Tachig.1) and exhibit a wide spectrum of biological actions such as smooth muscle contraction, sialogogic action and hypotension (Ersparmer, 1981). Until recently, substance P (SP)(X=Phe) has been the only known tachykinin shown to be present in the mammalian tissues. The accumulating evidence suggest t

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Biosynthesis of Somatostatin, Vasoactive Intestinal Polypeptide, and Thyrotropin Releasing Hormoneoactive intestinal polypeptide, and thyrotropin releasing hormone. Although each of these hormones is found in both the brain and gastrointestinal tract, their physiology is quite distinct. Furthermore, each peptide poses a unique set of problems for isolating and characterizing its gene and gene pr

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Oxytocin and Vasopressin Secretion: New Perspectivesacid residues and six of these are consistent throughout. The posterior pituitary hormones of about 50 species have been fully characterized. This is a small sample, representing about 0.1% of all vertebrate species, but it has allowed a number of principles to be established (Acher, 1980). Most spe

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