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Titlebook: Neuroendocrine Molecular Biology; G. Fink,A. J. Harmar,Kenneth W. McKerns Book 1986 Plenum Press, New York 1986 biology.development.endocr

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Biosynthesis of Somatostatin, Vasoactive Intestinal Polypeptide, and Thyrotropin Releasing Hormoneoducts. This review focuses on the different molecular approaches that we have used to characterize the precursors of these three peptides. It further describes the more general techniques that we are currently using to examine the expression of the three genes.
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Hybridization Histochemistry — Locating Gene Expressions of tissue (Hudson et al 1980; Coghlan et al 1981; Coghlan et al 1984; Hudson et al 1981; Jacobs et al 1983; Coghlan et al 1984). Later the same approach has been used by others to identify specific neurones in the hypothalamus (Gee et al 1983), to study the origin and fate of identified neurones i
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The Biosynthesis of LHRHequences of more than one biologically active molecule. For example, β-preprotachykinin incorporates the sequences of both substance P and substance K (Nawa ., 1983), and similarly oxytocin and arginine-vasopressin are synthesised within the same precursor molecule as their respective associated pro
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