Titlebook: Neurodegenerative Diseases; Clinical Aspects, Mo Daniela Galimberti,Elio Scarpini Book 2018Latest edition Springer International Publishing

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,Biomarkers for Alzheimer’s Disease and Frontotemporal Lobar Degeneration: Imaging,ng, structural and functional information on the brain tissue damage contributes to define the diagnosis of the major forms of dementia since their early clinical stages. From the research side, quantitative neuroimaging techniques have contributed in clarifying some critical pathophysiological aspe

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Genotypic and Phenotypic Heterogeneity in Amyotrophic Lateral Sclerosis,. Although genetic studies have partially elucidated the genetic background of the disease, a large part of ALS heritability is still missing. In this chapter, we discuss the major genes implicated in the pathogenesis of motor neuron diseases; the clinical, pathological, and genetic links between AL

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Lewy Body Dementia,h Lewy bodies (DLB) Consortium has refined its recommendations about the clinical and pathologic diagnosis of DLB, updating the previous report, which has been in widespread use for the last decade. The revised DLB consensus criteria now distinguish clearly between clinical features and diagnostic b

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Neurodevelopmental and Neurodegenerative Alterations in the Pathophysiology of Schizophrenia: Focusrespect to the etiology of schizophrenia, as for other major psychoses, the gene–environment interaction seems to be the most accredited model. In particular, alterations in the immune system have been repeatedly reported, involving both the unspecific and specific pathways of the immune system and

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,Parkinson’s Disease: Contemporary Concepts and Clinical Management,veral risk and protective factors have been recently identified, providing potential for the research and implementation of preventive strategies. Although most cases remain sporadic, various monogenic forms of PD have been described, including autosomal dominant (e.g., LRRK2, SNCA, VPS35, EIF4G1, C

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Neurodegeneration and Multiple Sclerosis,disabilities from cognitive decline, behavioral and mood disorders to problems with movement, co-ordination, and sensory dysfunction. Neurodegeneration is a major and growing public health issue which in its broadest sense embraces classical neurodegenerative disorders such as Alzheimer’s disease an

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Diagnosis of Frontotemporal Dementia, dementia. Advances in clinical, imaging, and molecular characterisation have increased the accuracy of the diagnosis of frontotemporal dementia. Updated diagnostic criteria have been developed and are now widely used. Recognition and accurate diagnoses of FTD subtypes will aid the neurologist in the management of patients.

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