Titlebook: Neurobiology of Opioids; Osborne F. X. Almeida,Toni S. Shippenberg Book 1991 Springer-Verlag Berlin Heidelberg 1991 CNS.Nucleotide.Rezepto

阴险

Book 1991ined by these various experimental approaches. The clinical relevance of recent findings, as well as future directions, in opioid research are also discussed. This volume thus represents a timely and invaluable sourcebook for researchers, clinicians, and students interested in opioids and peptidergic systems.

远地点

痛恨

Endogenous Opioid Systems in the Control of Pains, the conviction remains that there is a need for alternative modes of pain therapy and that an enhanced understanding of the operation of systems physiologically involved in the response to pain should facilitate the development of novel analgetic agents.

薄荷醇

f exogenous and endogenous opioids. Contributions by experts in the field discuss recent advances and provide systematic, up-to-date reviews of the physiology and pharmacology of opioids, as well as on the cellular and molecular mechanisms underlying opioid actions. In recognition of the diverse met

ARC

978-3-642-46662-5Springer-Verlag Berlin Heidelberg 1991

转折点

medieval

套索

Distribution of Opioids in Brain and Peripheral Tissuesthe “true” opioid? And what of Leu-ENK? Did it derive from a similarly large progenitor, a putative .-END with Leu in position five? Undoubtedly, such questions could have been eventually answered with biochemical, and later on, molecular biological tools. The answers, however, came surprisingly qui

机制

危机

Interactions Between Opioid Receptors and Guanine Nucleotide Regulatory Proteins in Intact Membranesffector systems. Although the general features of signal transduction pathways involving G-proteins were first elucidated for the regulation of adenyl cyclase and cyclic GMP phosphodiesterase, there is now compelling evidence that ion channels such as certain types of K. channels (Pfaffinger et al.