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Titlebook: Neuraxial Therapeutics; A Comprehensive Guid Tony Yaksh,Salim Hayek Book 2023 Springer Nature Switzerland AG 2023 Intrathecal Drug Delivery

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Jaroslav Pavel,Erika Kellerova,Jana Snopkovaeference models. This large coverage of practical optimization problems makes this text very useful to those working on and researching systems design. The intended audience includes industrial engineers, postg978-3-031-52461-5978-3-031-52459-2Series ISSN 1931-6828 Series E-ISSN 1931-6836
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Shelle A. Malkmus,Robert B. Boyd,Linda S. Sorkin,Tony L. Yakshtion, the section number. In cross references to other chapters the (latin) chapter number is put first. References to the bibliography are again by "author" plus "year" in parentheses. The bibliography again c978-3-642-05220-0978-3-642-05221-7Series ISSN 0179-3632 Series E-ISSN 2198-3712
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Tony L. Yaksh,Robert B. Boyd,Orion Paul Keifer Jr.tion, the section number. In cross references to other chapters the (latin) chapter number is put first. References to the bibliography are again by "author" plus "year" in parentheses. The bibliography again c978-3-642-05220-0978-3-642-05221-7Series ISSN 0179-3632 Series E-ISSN 2198-3712
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Emerging Insights into the Interstitial Distribution of Neuraxial Therapeutics via the Cerebrospinaggesting that CSF–interstitial exchange is anatomically organized, rapid, physiologically regulated, and impaired in the setting of CNS pathology. We then discuss the implications that these recent findings may have on the delivery of small molecules, biologics, viral-, and cell-based therapeutics to the CNS.
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Cerebrospinal Fluid, the Meninges, and the Subarachnoid Space,n in the CSF are reviewed in chapters “Emerging Insights into the Interstitial Distribution of Neuraxial Therapeutics via the Cerebrospinal Fluid Compartment” and “CSF Flow Dynamics in Relation to Intrathecal Drug Transport.”
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Formulation of Therapeutics for Neuraxial Infusion,r parenteral routes of administration. In this chapter, we review the specific anatomical and physiological features of the central nervous system that drive formulation principles for neuraxial delivery and detail excipient properties that are considered appropriate for solutions intended for spinal drug delivery.
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,‘resource to intrathecal therapies.Authored by worldwide le.This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics.  It reviews the historical evolution of this approach from its inception in the later 1800‘s to present day.   This amply referenced text cover
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