书目名称 | Neuraxial Therapeutics | 副标题 | A Comprehensive Guid | 编辑 | Tony Yaksh,Salim Hayek | 视频video | | 概述 | Covers basic principles, advanced clinical management, evidence-based approaches and translational research.Comprehensive, highly referenced,‘resource to intrathecal therapies.Authored by worldwide le | 图书封面 |  | 描述 | .This book is a comprehensive reference of the neuraxial route for the delivery of therapeutics. It reviews the historical evolution of this approach from its inception in the later 1800‘s to present day. This amply referenced text covers basic discussions of spinal anatomy, embryogenesis, neuraxial vascularity, cerebrospinal fluid flow dynamics and parenchymal molecule movement. The pharmacokinetic and pharmacodynamic properties of different intrathecal agents are explored in detail with particular reference to clinical correlates in pain and spasticity. Particular attention is paid to the issues relevant to preclinical models of intrathecal delivery and the assessment of spinal pathologies arising from acute and chronic intrathecal drug delivery. Chapters provide essential discussions of clinical aspects of patient care, including patient evaluation and screening, trialing and device management, troubleshooting problems and addressing complications, best practices, cost-effectiveness and future of the therapy. ..Clinicians and researchers who practice intrathecal therapy and study neuraxial mechanisms will find .Neuraxial Therapeutics., to be an invaluable guide to th | 出版日期 | Book 2023 | 关键词 | Intrathecal Drug Delivery System; Intrathecal pump; Intrathecal opioid; Intrathecal baclofen; Pain; Spast | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-39558-1 | isbn_softcover | 978-3-031-39560-4 | isbn_ebook | 978-3-031-39558-1 | copyright | Springer Nature Switzerland AG 2023 |
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