书目名称 | Nanoscale Imaging of Synapses |
副标题 | New Concepts and Opp |
编辑 | U. Valentin Nägerl,Antoine Triller |
视频video | |
概述 | Timeliness – Superresolution methods are beginning to transform neurobiological research.Relevance – Progress in synapse research hinges on advances in superresolution imaging.Competence – Chapters ar |
丛书名称 | Neuromethods |
图书封面 |  |
描述 | Synapses underlie rapid and flexible neural communication in the brain and they hold the key to understanding higher brain functions in health and disease. Because they are very small and highly dynamic, it is very difficult to study them with traditional techniques. Fortunately, recent ground-breaking advances in optical microscopy (e.g. STED, PALM, STORM, SIM) have greatly improved our ability to image living synapses at the nanoscale, even down to the level of single molecules. The proposed volume brings together leading researchers to review these exciting new techniques and their application in neurobiological research. It will explain and discuss the basic principles behind the various superresolution modalities, how they are implemented, what their scope and limitations are etc. In addition, several key research discoveries on synapses enabled by these novel approaches will be highlighted. |
出版日期 | Book 2014 |
关键词 | live-cell fluorescence microsopy; nanoscopy; neurons and glia; physiology; synapses |
版次 | 1 |
doi | https://doi.org/10.1007/978-1-4614-9179-8 |
isbn_softcover | 978-1-4939-4918-2 |
isbn_ebook | 978-1-4614-9179-8Series ISSN 0893-2336 Series E-ISSN 1940-6045 |
issn_series | 0893-2336 |
copyright | Springer Science+Business Media New York 2014 |